Symposium Schedule
Friday, June 18, 2010
| Session Chair: Raji Edayathumangalam |
| 8:30 | | Introduction |
|
| 8:45 | | Opening Remarks -- Louise Johnson |
| 9:15 | | Diane Joseph-McCarthy |
| | "Fragments for Drug Discovery" |
| 9:45 | | Axel Brunger |
| | "Reconstitution of Calcium Triggered Synaptic Vesicle Fusion" |
| | |
| 10:15 | | Coffee |
| Session Chair: Jared Auclair |
| 10:45 | | Steve Almo |
| | "Sequence, Structure, Function, Immunity" |
| 11:15 | | Roland Strong |
| | "Why Things are Red: Siderocalin, from Siderophores & Bacterial Virulence to Apoptosis & Cancer" |
| 11:45 | | Ken Gabbay |
| | "From Aldose Reductase to Osterix: Diabetes to Osteoporosis" |
| 12:15 | | Lunch |
| Session Chair: Ce Feng Liu |
| 1:45 | | Connie Jeffery |
| | "Phosphoglucose Isomerase and Other Moonlighting Proteins" |
| 2:15 | | Tom Alber |
| | "Oldies but goodies: B-values, temperature, FDR and noise" |
| 2:45 | | Coffee |
| Session Chair: Paul Hubbard |
| 3:15 | | Steve Burley |
| | "Structure-Guided Fragment Based Drug Discovery Using a Structural Genomics Platform" |
| 3:45 | | Martin Karplus |
| | "How Proteins Work: Insights from Simulations" |
| 4:15 | | Closing Remarks |
| 6:00 | | Reception/Social |
| 7:00 | | Dinner |
Saturday, June 19, 2010
| 8:30 | | Introduction |
|
| 8:45 | | Opening Remarks -- Barbara Seaton |
| 9:15 | | Charlie Brenner |
| | "New Steps in NAD Metabolism: Regulation of Life, Death, and Aging" |
| 9:45 | | Emil Pai |
| | "The Ever-Growing Epitope of an Anti-HIV-1 Antibody" |
| 10:15 | | Coffee |
| 10:45 | | Ann Stock |
| | "Conformational Dynamics: A Target for Regulating Protein Activity" |
| 11:15 | | Carla Mattos |
| | "Allosteric Modulation of Ras: A Direct Role for Glutamine 61 in Catalysis" |
| 11:45 | | John Kuriyan |
| | "How DNA Polymerase Clamp Loaders Work" |
| 12:15 | | Lunch |
| Session Chair: Melissa Landon |
| 1:45 | | Lynne Howell |
| | "The Good, the Bad and the Slimy: Biosynthesis and Export of Bacterial Exopolysaccharides" |
| 2:15 | | David Rose |
| | Mind the GAP: Glycosidases from Lysozyme to Human Health |
| 2:45 | | Coffee |
| Session Chair: Quyen Hoang |
| 3:15 | | Barry Stoddard |
| | "Homing Endonucleases: Structures, Engineering, and Application to Genome Engineering" |
| 3:45 | | Elias Lolis |
| | "Non-Competitive Inhibitors of Macrophage Migration Inhibitory Factor: an Induced-Fit Allosteric Mechanism" |
| 4:15 | | Closing Remarks -- Greg & Dagmar |
