From Sequence to Consequence: Celebrating
30 years of Science with Dagmar Ringe and Greg Petsko

June 18-19, 2010
Shapiro Theater, Shapiro Campus Center
Brandeis University

Portrait of Dagmar
Portrait of Greg


Latest news:

June 14, 2010:
Pre-symposium happy hour! If you are in town on Thursday evening, please come join us for some free drinks and finger food at the The Skellig from 6PM onwards...


More info:

Want to know more about Greg and Dagmar? Here are some helpful links:

- PR Lab
- Greg Petsko
- Dagmar Ringe

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Symposium Schedule

Friday, June 18, 2010

Session Chair: Raji Edayathumangalam
8:45Opening Remarks -- Louise Johnson
9:15Diane Joseph-McCarthy
"Fragments for Drug Discovery"
9:45Axel Brunger
"Reconstitution of Calcium Triggered Synaptic Vesicle Fusion"

Session Chair: Jared Auclair
10:45Steve Almo
"Sequence, Structure, Function, Immunity"
11:15Roland Strong
"Why Things are Red: Siderocalin, from Siderophores & Bacterial Virulence to Apoptosis & Cancer"
11:45Ken Gabbay
"From Aldose Reductase to Osterix: Diabetes to Osteoporosis"

Session Chair: Ce Feng Liu
1:45Connie Jeffery "Phosphoglucose Isomerase and Other Moonlighting Proteins" 2:15Tom Alber "Oldies but goodies: B-values, temperature, FDR and noise" 2:45Coffee
Session Chair: Paul Hubbard
3:15Steve Burley
"Structure-Guided Fragment Based Drug Discovery Using a Structural Genomics Platform"
3:45Martin Karplus
"How Proteins Work: Insights from Simulations"
4:15Closing Remarks

Saturday, June 19, 2010

Session Chair: Xu Simon
8:45Opening Remarks -- Barbara Seaton
9:15Charlie Brenner
"New Steps in NAD Metabolism: Regulation of Life, Death, and Aging"
9:45Emil Pai
"The Ever-Growing Epitope of an Anti-HIV-1 Antibody"

Session Chair: Dali Liu
10:45Ann Stock
"Conformational Dynamics: A Target for Regulating Protein Activity"
11:15Carla Mattos
"Allosteric Modulation of Ras: A Direct Role for Glutamine 61 in Catalysis"
11:45John Kuriyan
"How DNA Polymerase Clamp Loaders Work"

Session Chair: Melissa Landon
1:45Lynne Howell
"The Good, the Bad and the Slimy: Biosynthesis and Export of Bacterial Exopolysaccharides"
2:15David Rose
Mind the GAP: Glycosidases from Lysozyme to Human Health

Session Chair: Quyen Hoang
3:15Barry Stoddard
"Homing Endonucleases: Structures, Engineering, and Application to Genome Engineering"
3:45Elias Lolis
"Non-Competitive Inhibitors of Macrophage Migration Inhibitory Factor: an Induced-Fit Allosteric Mechanism"
4:15Closing Remarks -- Greg & Dagmar