Home > M.R. Bauer Foundation > 1995 Summary Report > Sacha Nelson, Ph.D.
Scientific Retreat
Sacha Nelson, Ph.D.
Assistant Professor of Biology
Brandeis University
Waltham, Massachusetts
May 30, 1995

Orientation Selectivity and Recurrent Excitation in the Visual Cortex

Neurons in the visual cortex respond selectively to particular features or patterns in the visual world. The objective of our research is to understand the cellular and circuit-level properties that underlie this selectivity.

We employ two approaches to this problem: a "bottom-up" approach in which we try to understand the basic cellular and synaptic building blocks of cortical function in an in vitro slice preparation, and a "top-down" approach in which we study the responses of neurons to sensory stimuli in vivo.

This talk discussed our ex-periments concerning the way in which successive synaptic inputs are integrated over time, and the spatial aspects of synaptic integration.

 


 

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