What we study: 

We study the molecular basis of sensory transduction and behavior by investigating the molecular detectors and neural circuits that sense temperature and chemicals. We study thermal and chemical sensation because it allows us to address fundamental questions in neuroscience, molecular biology, biophysics, and evolution, while providing insights relevant to human health and the development of new technologies for controlling neuronal activity.

A major focus of the lab is on the molecules and neurons regulating thermal and chemical sensation in flies and mosquitoes, emphasizing the ion channels involved in sensory transduction.  These studies inform a second area of the lab, the development of "thermogenetic" tools for remote-control activation of neurons using temperature. Finally, we are investigating how thermal and chemical detectors have evolved and naturally vary in animals from insects to vertebrates.

Where we work:

Our lab is part of the National Center for Behavioral Genomics in the Biology Department at Brandeis University.  Brandeis has a vibrant, tightly knit molecular genetics and neuroscience community. We interact extensively with other labs at Brandeis and at nearby institutions. The critical mass of scientists at Brandeis and around Boston is a tremendous resource, starting with our immediate neighbors in the labs of Michael Rosbash, Piali Sengupta and Leslie Griffith, and extending to NIH-funded collaborations with the labs of Aravi Samuel at Harvard University and Flaminia Catteruccia at the Harvard School of Public Health.

Brandeis is located on the west side of Boston. It is readily accessible by public transportation and car from all over Boston and its suburbs. Members of the lab live in Boston, Cambridge, Newton, Somerville, Waltham, and Worcester.

Who supports us:

The lab is supported by funding from the National Science Foundation, the National Institute of Allergy and Infectious Diseases and the National Institute of General Medical Sciences.

The lab is actively seeking talented, highly motivated individuals to join us. Post-doctoral applicants are encouraged to contact P.G. by e-mail. Please include a CV and contact information for three references.

 

Welcome to the Garrity Lab

Behavior

 

Physiology

 

Molecular genetics

 

Evolution