The goal of our research is to understand the molecular basis of actin cytoskeleton remodeling events in yeast and mammalian cells, and how functions of the actin and
microtubule cytoskeletons are coordinated. We take a multidisciplinary approach combining genetics, biochemistry, structural biology, single molecule analysis, and
live-cell imaging to obtain a quantitative view of the molecular mechanisms and dynamics involved.
actin filaments by TIRF microscopy
formin and actinin in isolated rat cardiac myocyte
dynamic microtubules by TIRF microscopy
actin, microtubules and DNA
in budding yeast cytokinesis
direction of movement
GFP, actin and
microtubules in motile cells
pyrene-actin assembled by Bnr1 formin
bundled actin filaments by EM
Actin cables during budding
Mouse over images for information
10/28/2011
Casey's mini-review on actin branching/debranching published in CSK.
09/07/2011
Brian's paper defining Bud6 as a nucleation-promoting factor is out at MBoC.
08/16/2011
Melissa's paper on regulation of the formin Bnr1 by Smy1 is out at Developmental Cell.
07/29/2011
Kristin's last day as Goode lab tech. Good luck at Harvard!
07/08/2011
Sasha Bear got a haircut! Visit the lab to see her new 'do.
06/10/2011
We welcome REU students Veronika Kivenson and Long Le to the lab for the summer.
05/25/2011
Julian passed his Inside qualifying exam and was awarded an AHA fellowship on the same day!
05/18/2011
Congratulations to Adam on passing his Outside qualifying exam!
05/05/2011
Welcome to the Goode Lab's newest member: MCB grad student Adam Johnston.
