Graduate Program in Biochemistry and Biophysics

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Application Deadlines:

2019-2020 academic year

The deadline for Ph.D. applications is 12/1/18

The M.S. application deadline is rolling through 5/1/19

Research Facilities

Brandeis University operates several specialized research facilities in the Life Sciences. The electron microscopy facility houses four electron microscopes, three of which are equipped for low-dose, high-resolution cryo-microscopy. In particular, 200 and 300-kV field emission electron cryo-microscopes were installed in 2010 and 2005, respectively. In addition, there are two film scanners for digitizing electron micrographs, a computer-farm for processing images, cold stages for the microscopes, fast-freezing apparatuses, and other ancillary equipment.

The new science building houses a modern mass spectrometry facility, including three mass spectrometers: a 9.4-T FTMS, a MALDI-TOF, and an ion trap MS. Interfaced to these is an HPLC system and a spotting robot for in-gel digests. Two x-ray diffraction facilities for protein crystallography and one small-molecule diffraction setup are also maintained in the Science Complex.

The Science Complex buildings house five nuclear magnetic resonance spectrometers used for chemical analysis, structure determination, and macromolecular dynamics. A 400 MHz machine is used for small-molecule analysis. A 500 MHz machine is dedicated to protein structure and general biochemical applications. A second home-built 500 MHz machine is used primarily for technique development. A 600 MHz instrument is used for high-resolution structure determination and protein dynamics. Finally, a 800 MHz spectrometer was installed in late 2005. These spectrometers employ modern probes for 1H,13C, and 15N (triple resonance, field gradients, etc.); probes for special applications requiring 31P, 35Cl, and 205Tl are also in use on these machines.

 

 
415 South Street, Waltham, MA 02453 (781) 736-2000