MCB Faculty Publications -- 2011

• Molecular Organization of Drosophila Neuroendocrine Cells by Dimmed. Park D, Hadžic T, Yin P, Rusch J, Abruzzi K, Rosbash M, Skeath JB, Panda S, Sweedler JV, Taghert PH. Curr Biol. 2011 Aug 30. [Epub ahead of print]

• A new twist on clock protein phosphorylation: a conformational change leads to protein degradation. Menet JS, Rosbash M. Mol Cell. 2011 Sep 2;43(5):695-7.

• Nothing to do and all day to do it in. Petsko GA. Genome Biol. 2011 Aug 31;12(8):126.

• Mechanism and cellular function of Bud6 as an actin nucleation-promoting factor. Graziano BR, Dupage AG, Michelot A, Breitsprecher D, Moseley JB, Sagot I, Blanchoin L, Goode BL. Mol Biol Cell. 2011 Aug 31. [Epub ahead of print]

• Allosteric activation via kinetic control: Potassium accelerates a conformational change in IMP dehydrogenase. Riera TV, Zheng L, Josephine HR, Min D, Yang W, Hedstrom L. Biochemistry. 2011 Aug 26. [Epub ahead of print]

• Herding CATS. Petsko GA. Sci Transl Med. 2011 Aug 24;3(97):97cm24.

• Two alternating motor programs drive navigation in Drosophila larva. Lahiri S, Shen K, Klein M, Tang A, Kane E, Gershow M, Garrity P, Samuel AD. PLoS One. 2011;6(8):e23180. Epub 2011 Aug 15.

• Proteostasis and Movement Disorders: Parkinson's Disease and Amyotrophic Lateral Sclerosis. Bosco DA, Lavoie MJ, Petsko GA, Ringe D. Cold Spring Harb Perspect Biol. 2011 Aug 15. pii: cshperspect.a007500v1. doi: 10.1101/cshperspect.a007500. [Epub ahead of print]

• The Myosin passenger protein smy1 controls actin cable structure and dynamics by acting as a formin damper.  Chesarone-Cataldo M, Guérin C, Yu JH, Wedlich-Soldner R, Blanchoin L, Goode BL. Dev Cell. 2011 Aug 16;21(2):217-30.

• Degeneracy and Neuromodulation among Thermosensory Neurons Contribute to Robust Thermosensory Behaviors in Caenorhabditis elegans. Beverly M, Anbil S, Sengupta P. J Neurosci. 2011 Aug 10;31(32):11718-27.

• Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules. Sanchez A, Osborne ML, Friedman LJ, Kondev J, Gelles J. EMBO J. 2011 Aug 9. doi: 10.1038/emboj.2011.273. [Epub ahead of print]

• Mrs. Professor. Cohen C. J Biol Chem. 2011 Jul 28. [Epub ahead of print] No abstract available.

• Emerging themes in GABAergic synapse development. Kuzirian MS, Paradis S. Prog Neurobiol. 2011 Sep 15;95(1):68-87. Epub 2011 Jul 20.

• Food of the dogs. Petsko GA. Genome Biol. 2011 Jul 25;12(7):122.

• Cilia-like beating of active microtubule bundles. Sanchez T, Welch D, Nicastro D, Dogic Z. Science. 2011 Jul 22;333(6041):456-9.

• When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders. Menet JS, Rosbash M. Curr Opin Neurobiol. 2011 Jul 5. [Epub ahead of print]

• Risky business. Petsko GA. Genome Biol. 2011 Jun 30;12(6):119

• Building blocks of the nexin-Dynein regulatory complex in chlamydomonas flagella. Lin J, Tritschler D, Song K, Barber CF, Cobb JS, Porter ME, Nicastro D. J Biol Chem. 2011 Aug 19;286(33):29175-91. Epub 2011 Jun 23.

• Imaging analysis of clock neurons reveals light buffers the wake-promoting effect of dopamine. Shang Y, Haynes P, Pírez N, Harrington KI, Guo F, Pollack J, Hong P, Griffith LC, Rosbash M. Nat Neurosci. 2011 Jun 19;14(7):889-95. doi: 10.1038/nn.2860.

• Cell compatible trimethoprim-decorated iron oxide nanoparticles bind dihydrofolate reductase for magnetically modulating focal adhesion of mammalian cells. Long MJ, Pan Y, Lin HC, Hedstrom L, Xu B. J Am Chem Soc. 2011 Jul 6;133(26):10006-9.

• β-Galactosidase-instructed formation of molecular nanofibers and a hydrogel. Zhao F, Weitzel CS, Gao Y, Browdy HM, Shi J, Lin HC, Lovett ST, Xu B. Nanoscale. 2011 Jun 7;3(7):2859-61. Epub 2011 Jun 2.

• In praise of model organisms. Petsko GA. Genome Biol. 2011 May 30;12(5):115.

• The CSC is required for complete radial spoke assembly and wild-type ciliary motility. Dymek EE, Heuser T, Nicastro D, Smith EF. Mol Biol Cell. 2011 Jul;22(14):2520-31. Epub 2011 May 25.

• Weakly acidic, but strongly irritating: TRPA1 and the activation of nociceptors by cytoplasmic acidification. Garrity PA. J Gen Physiol. 2011 Jun;137(6):489-91.

• Cell type-specific transcriptomics in the brain.  Okaty BW, Sugino K, Nelson SB. J Neurosci. 2011 May 11;31(19):6939-43.

• The blue marble. Petsko GA. Genome Biol. 2011 Apr 28;12(4):112.

• Circadian biology: the supporting cast takes on a starring role. Griffith LC. Curr Biol. 2011 May 10;21(9):R313-4.

• Time-of-flight neutron diffraction study of bovine γ-chymotrypsin at the Protein Crystallography Station. Lazar LM, Fisher SZ, Moulin AG, Kovalevsky A, Novak WR, Langan P, Petsko GA, Ringe D. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):587-90. Epub 2011 Apr 27.

• A yeast model of FUS/TLS-dependent cytotoxicity. Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH Jr, Lindquist S, Ringe D, Petsko GA. PLoS Biol. 2011 Apr;9(4):e1001052. Epub 2011 Apr 26.

• Spatial regulation of Cdc55-PP2A by Zds1/Zds2 controls mitotic entry and mitotic exit in budding yeast. Rossio V, Yoshida S. J Cell Biol. 2011 May 2;193(3):445-54.

• The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors. Hedstrom L, Liechti G, Goldberg JB, Gollapalli DR. Curr Med Chem. 2011;18(13):1909-18.

• The GTPase Rem2 regulates synapse development and dendritic morphology. Ghiretti AE, Paradis S. Dev Neurobiol. 2011 May;71(5):374-89. doi: 10.1002/dneu.20868.

• A presynaptic endosomal trafficking pathway controls synaptic growth signaling. Rodal AA, Blunk AD, Akbergenova Y, Jorquera RA, Buhl LK, Littleton JT. J Cell Biol. 2011 Apr 4;193(1):201-17.

• The walking dead. Petsko GA. Genome Biol. 2011 Mar 31;12(3):108.

• Insights into mutagenesis using Escherichia coli chromosomal lacZ strains that enable detection of a wide spectrum of mutational events. Seier T, Padgett DR, Zilberberg G, Sutera VA Jr, Toha N, Lovett ST. Genetics. 2011 Jun;188(2):247-62. Epub 2011 Mar 24.

• Control of prestimulus activity related to improved sensory coding within a discrimination task.  Yoshida T, Katz DB. J Neurosci. 2011 Mar 16;31(11):4101-12.

• There is a sanity clause. Petsko GA. Genome Biol. 2011 Feb 25;12(2):105.

• Preserving some sanity. Petsko GA. Genome Biol. 2011 Jan 31;12(1):102.

• Cellular reprogramming: chromatin puts on the brake. Sengupta P, Schedl T. Curr Biol. 2011 Feb 22;21(4):R157-9.

• The formin DAD domain plays dual roles in autoinhibition and actin nucleation. Gould CJ, Maiti S, Michelot A, Graziano BR, Blanchoin L, Goode BL. Curr Biol. 2011 Mar 8;21(5):384-90. Epub 2011 Feb 17.

• Regulation of response properties and operating range of the AFD thermosensory neurons by cGMP signaling. Wasserman SM, Beverly M, Bell HW, Sengupta P. Curr Biol. 2011 Mar 8;21(5):353-62.

• A quantitative comparison of cell-type-specific microarray gene expression profiling methods in the mouse brain. Okaty BW, Sugino K, Nelson SB. PLoS One. 2011 Jan 27;6(1):e16493.

• Specific biotinylation of IMP dehydrogenase. Hoefler BC, Gollapalli DR, Hedstrom L. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1363-5. Epub 2011 Jan 14.

• Real-time analysis of double-strand DNA break repair by homologous recombination. Hicks WM, Yamaguchi M, Haber JE. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3108-15. Epub 2011 Feb 3.

• Design and verification of a highly reliable Linear-After-The-Exponential PCR (LATE-PCR) assay for the detection of African swine fever virus. Ronish B, Hakhverdyan M, Ståhl K, Belák S, Leblanc N, Wangh L. J Virol Methods. 2011 Mar;172(1-2):8-15. Epub 2010 Dec 15.

• Activity-dependent changes in the firing properties of neocortical fast-spiking interneurons in the absence of large changes in gene expression. Miller MN, Okaty BW, Kato S, Nelson SB. Dev Neurobiol. 2011 Jan 1;71(1):62-70. doi: 10.1002/dneu.20811.

• Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Brown JH, Kumar VS, O'Neall-Hennessey E, Reshetnikova L, Robinson H, Nguyen-McCarty M, Szent-Györgyi AG, Cohen C. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):114-9. Epub 2010 Dec 13.

• Toxicity and tolerance mechanisms for azidothymidine, a replication gap-promoting agent, in Escherichia coli. Cooper DL, Lovett ST. DNA Repair (Amst). 2011 Mar 7;10(3):260-70. Epub 2010 Dec 10.

• Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Brown JH, Kumar VS, O'Neall-Hennessey E, Reshetnikova L, Robinson H, Nguyen-McCarty M, Szent-Györgyi AG, Cohen C. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):114-9. Epub 2010 Dec 13.

• Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination. Kim JA, Hicks WM, Li J, Tay SY, Haber JE. Mol Cell Biol. 2011 Feb;31(3):507-16. Epub 2010 Dec 6.

• Central regulation of locomotor behavior of Drosophila melanogaster depends on a CASK isoform containing CaMK-like and L27 domains. Slawson JB, Kuklin EA, Ejima A, Mukherjee K, Ostrovsky L, Griffith LC. Genetics. 2011 Jan;187(1):171-84. Epub 2010 Nov 8.

• LATE-PCR and allied technologies: real-time detection strategies for rapid, reliable diagnosis from single cells. Pierce KE, Wangh LJ. Methods Mol Biol. 2011;688:47-66.

Edited: 9/6/11