The Griffith lab behavior
studies can be grouped into five separate topics.
Courtship Conditioning
How experience influences
behavior is a central question in neuroscience. The ability to manipulate
CaMKII activity in vivo is a prerequisite for the study of the
role of the enzyme in behavior. (more
information)
Anatomical Mapping of
Behavioral Circuits
One of the most powerful
techniques available for the study of the molecular basis of behavior
is the ability to generate animals with tissue-specific disruptions
of second messenger pathways (more
information).
Bidirectional Modulation
of Behavior with CaMKII
More recently, we have developed
a system that enables us to control transgene expression in both spatial
and temporal domains (Mehren and Griffith, 2004) (more
information).
Dissection of the Chemical
Cues Underlying Courtship Learning
The conditioned stimulus
(CS) for courtship conditioning has been assumed for many years to be
a component of the female's cuticular hydrocarbon (more
information).
Motor Behaviors
We are also interested in
the generation of larval motor behaviors (more
information).