Recent Haber Lab Publications
This link may be used to view a list of recent publications from PubMed.


Lemos, B.R., Kaplan, A.C., Bae, J.E., Ferrazzoli, A.E., Kuo, J., Anand, R.P., Waterman, D.P., and Haber, J.E. (2018). CRISPR/Cas9 cleavages in budding yeast reveal templated insertions and strand-specific insertion/deletion profiles. Proceedings of the National Academy of Sciences of the United States of America.


Gallagher, D.N., and Haber, J.E. (2017). Repair of a Site-Specific DNA Cleavage: Old-School Lessons for Cas9-Mediated Gene Editing. ACS Chem Biol. Nov Epub

Botchkarev, V.V., Jr., and Haber, J.E. (2018). Functions and regulation of the Polo-like kinase Cdc5 in the absence and presence of DNA damage. ACS Chemical Biology 64, 87-96.

Wang, R.W., Lee, C.S., and Haber, J.E. (2017). Position effects influencing intrachromosomal repair of a double-strand break in budding yeast. Current Genetics 12, e0180994.

Botchkarev, V.V., Jr., Garabedian, M.V., Lemos, B., Paulissen, E., and Haber, J.E. (2017). The budding yeast Polo-like kinase localizes to distinct populations at centrosomes during mitosis. PloS One 28, 1011-1020.

Eapen, V.V., Waterman, D.P., Bernard, A., Schiffmann, N., Sayas, E., Kamber, R., Lemos, B., Memisoglu, G., Ang, J., Mazella, A., et al. (2017). A pathway of targeted autophagy is induced by DNA damage in budding yeast. Proc Natl Acad Sci U S A. 114, E1158-e1167.


Mehta A, Beach A, Haber JE. (2016). Homology Requirements and Competition between Gene Conversion and Break-Induced Replication during Double-Strand Break Repair. Mol Cell. Dec 22.

Avsaroglu B, Bronk G, Li K, Haber JE, Kondev J. (2016). Chromosome-refolding model of mating-type switching in yeast. Proc Natl Acad Sci U S A. 2016 Oct 24.

Haber JE. (2016). A Life Investigating Pathways That Repair Broken Chromosomes. Annu Rev Genet. 50:1-28.

Tsabar M, Hicks WM, Tsaponina O, Haber JE. (2016). Re-establishment of nucleosome occupancy during double-strand break repair in budding yeast.
DNA Repair 47:21-29.

Jasin M, Haber JE. (2016). The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.
DNA Repair (Amst). 44:6-16.

Tsabar M, Waterman DP, Aguilar F, Katsnelson L, Eapen VV, Memisoglu G, Haber JE. (2016). Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair. Genes Dev. 30:1211-24.

Tsabar M, Haase J, Harrison B, Snider CE, Eldridge B, Kaminsky L, Hine RM, Haber JE, Bloom K. (2016). A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere. PLoS Genet. 29;12(4):e1006021.

Haber, J.E. (2016). The rule of three. Nature reviews Molecular Cell Biology 17, 333.

Jain, S., Sugawara, N., and Haber, J.E. (2016a). Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae. PLoS Genetics 12, e1005976.

Jain, S., Sugawara, N., Mehta, A., Ryu, T., and Haber, J.E. (2016b). Sgs1 and Mph1 Helicases Enforce the Recombination Execution Checkpoint During DNA Double-Strand Break Repair in Saccharomyces cerevisiae. Genetics 203, 667-675.

Jasin, M., and Haber, J.E. (2016). The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair. DNA Repair 44, 6-16.

Klionsky, D.J., Abdelmohsen, K., Abe, A., Abedin, M.J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C.M., Adams, P.D., Adeli, K., et al. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1-222.

Lee, C.S., Wang, R.W., Chang, H.H., Capurso, D., Segal, M.R., and Haber, J.E. (2016). Chromosome position determines the success of double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America 113, E146-154.

Nakajima, Y., and Haber, J.E. (2016). Chromosomes at loose ends. Nature Cell Biology 18, 257-259.

Tsabar, M., Haase, J., Harrison, B., Snider, C.E., Eldridge, B., Kaminsky, L., Hine, R.M., Haber, J.E., and Bloom, K. (2016a). A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere. PLoS Genetics 12, e1006021.

Tsabar, M., Waterman, D.P., Aguilar, F., Katsnelson, L., Eapen, V.V., Memisoglu, G., and Haber, J.E. (2016b). Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair. Genes & Development 30, 1211-1224.

Yimit, A., Kim, T., Anand, R.P., Meister, S., Ou, J., Haber, J.E., Zhang, Z., and Brown, G.W. (2016). MTE1 Functions with MPH1 in Double-Strand Break Repair. Genetics 203, 147-157.


Ferrari, M., Dibitetto, D., De Gregorio, G., Eapen, V.V., Rawal, C.C., Lazzaro, F., Tsabar, M., Marini, F., Haber, J.E., and Pellicioli, A. (2015). Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break. PLoS Genetics 11, e1004928.

Haber, J.E. (2015a). Deciphering the DNA Damage Response. Cell 162, 1183-1185.

Haber, J.E. (2015b). TOPping off meiosis. Molecular cell 57, 577-581.

Lee, C.S., and Haber, J.E. (2015). Mating-type Gene Switching in Saccharomyces cerevisiae. Microbiology Spectrum 3, MDNA3-0013-2014.

Tsabar, M., Eapen, V.V., Mason, J.M., Memisoglu, G., Waterman, D.P., Long, M.J., Bishop, D.K., and Haber, J.E. (2015a). Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2. Nucleic Acids Research 43, 6889-6901.

Tsabar, M., Mason, J.M., Chan, Y.L., Bishop, D.K., and Haber, J.E. (2015b). Caffeine inhibits gene conversion by displacing Rad51 from ssDNA. Nucleic Acids Research 43, 6902-6918.


Anand RP, Tsaponina O, Greenwell PW, Lee CS, Du W, Petes TD, Haber JE (2014) Chromosome rearrangements via template switching between diverged repeated. Genes Dev 28: 2394-2406.

Avsaroglu B, Bronk G, Gordon-Messer S, Ham J, Bressan DA, Haber JE, Kondev J (2014) Effect of chromosome tethering on nuclear organization in yeast. PLoS One 9: e102474 DOI: 10.1371/journal.pone.0102474.

Braberg H, Alexander R, Shales M, Xu J, Franks-Skiba KE, Wu Q, Haber JE, Krogan NJ (2014) Quantitative analysis of triple-mutant genetic interactions. Nat Protoc 9: 1867-1881.

Costantino L, Sotiriou Sk Fau - Rantala JK, Rantala Jk Fau - Magin S, Magin S Fau - Mladenov E, Mladenov E Fau - Helleday T, Helleday T Fau - Haber JE, Haber Je Fau - Iliakis G, Iliakis G Fau - Kallioniemi OP, Kallioniemi Op Fau - Halazonetis TD, Halazonetis TD (2014) Break-induced replication repair of damaged forks induces genomic duplications in. Science 343: 88-91.

Lee CA-O, Lee K, Legube G, Haber JE (2014) Dynamics of yeast histone H2A and H2B phosphorylation in response to a. Nat Struct Mol Biol 21: 103-109

Mehta A, Haber JE (2014) Sources of DNA double-strand breaks and models of recombinational DNA repair. Cold Spring Harb Perspect Biol Aug 7; 6(9).

Tsaponina O, Haber JE (2014) Frequent Interchromosomal Template Switches during Gene Conversion in S. Mol Cell 55: 615-625.


Haber JE, Braberg H Fau - Wu Q, Wu Q Fau - Alexander R, Alexander R Fau - Haase J, Haase J Fau - Ryan C, Ryan C Fau - Lipkin-Moore Z, Lipkin-Moore Z Fau - Franks-Skiba KE, Franks-Skiba Ke Fau - Johnson T, Johnson T Fau - Shales M, Shales M Fau - Lenstra TL, Lenstra Tl Fau - Holstege FCP, Holstege Fc Fau - Johnson JR, Johnson Jr Fau - Bloom K, Bloom K Fau - Krogan NJ, Krogan NJ (2013) Systematic triple-mutant analysis uncovers functional connectivity between. Cell Rep 3: 2168-2178
Liebman SW, Haber JE (2013) Retrospective. Fred Sherman (1932-2013). Science 342: 1059

Anand RP, Lovett ST, Haber JE. (2013) Break-Induced DNA Replication. Cold Spring Harb Perspect Biol. Jul 23.

Saini N, Ramakrishnan S, Elango R, Ayyar S, Zhang Y, Deem A, Ira G, Haber JE, Lobachev KS, Malkova A. (2013) Migrating bubble during break-induced replication drives conservative DNA synthesis. Nature 17;502(7471):389-92

Anand RP, Lovett ST, Haber JE. (2013) Break-Induced DNA Replication. Cold Spring Harb Perspect Biol. Jul 23.

Haber JE, Braberg H, Wu Q, Alexander R, Haase J, Ryan C, Lipkin-Moore Z, Franks-Skiba KE, Johnson T, Shales M, Lenstra TL, Holstege FC, Johnson JR, Bloom K, Krogan NJ. (2013) Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation. Cell Rep. 3(6):2168-78.

Tsabar M, Haber JE. (2013) Chromatin modifications and chromatin remodeling during DNA repair in budding yeast. Curr Opin Genet Dev. 23(2):166-73

Eapen VV, Haber JE. (2013) DNA damage signaling triggers the cytoplasm-to-vacuole pathway of autophagy to regulate cell cycle progression. Autophagy. 9(3):440-1

Dotiwala F, Eapen VV, Harrison JC, Arbel-Eden A, Ranade V, Yoshida S, Haber JE. (2013) DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase. Proc Natl Acad Sci U S A. 110(1):E41-9


Dotiwala F, Eapen VV, Harrison JC, Arbel-Eden A, Ranade V, Yoshida S, Haber JE. (2012) DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase. Proc Natl Acad Sci U S A 110(1):E41-9.

Eapen VV, Sugawara N, Tsabar M, Wu WH, Haber JE. (2012) The Saccharomyces cerevisiae chromatin remodeler Fun30 regulates DNA end resection and checkpoint deactivation. Mol Cell Biol. 32:4727-40

Haber JE. (2012) Mating-type genes and MAT switching in Saccharomyces cerevisiae. Genetics. 191(1):33-64

Li J, Coic E, Lee K, Lee CS, Kim JA, Wu Q, Haber JE. (2012) Regulation of budding yeast mating-type switching donor preference by the FHA domain of Fkh1. PLoS Genet. 8(4):e1002630

Malkova A, Haber JE. (2012) Mutations arising during repair of chromosome breaks. Annu Rev Genet. 46:455-73

Sugawara N, Haber JE. (2012) Monitoring DNA recombination initiated by HO endonuclease. Methods Mol Biol. 920:349-70.


Coïc E, Martin JS, Ryu T, Tay SY, Kondev J, Haber JE. (2011) Dynamics of Homology Searching During Gene Conversion in Saccharomyces cerevisiae Revealed by Donor Competition. Genetics. 2011 Sep 27

Hicks WM, Yamaguchi M, Haber JE. (2011) Real-time analysis of double-strand DNA break repair by homologous recombination. Proc Natl Acad Sci U S A. 108(8):3108-15.

Kim JA, Hicks WM, Li J, Tay SY, Haber JE.. (2011) Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination. Mol Cell Biol. 31(3):507-16


Hicks WM, Kim M, Haber JE. (2010) Increased mutagenesis and unique mutation signature associated with mitotic gene conversion. Science. 2;329(5987):82-5, 22;330(6003):448.

Lydeard JR, Lipkin-Moore Z, Jain S, Eapen VV, Haber JE. (2010) Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends. PLoS Genet. 27;6(5).

Lydeard JR, Lipkin-Moore Z, Sheu YJ, Stillman B, Burgers PM, Haber JE. (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev. 1;24(11):1133-44.

Toh GW, Sugawara N, Dong J, Toth R, Lee SE, Haber JE, Rouse J. (2010) Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails. DNA Repair (Amst). 4;9(6):718-26.

Saponaro M, Callahan D, Zheng X, Krejci L, Haber JE, Klein HL, Liberi G. (2010) Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repair. PLoS Genet. 26;6(2).


Dotiwala F, Harrison JC, Jain S, Sugawara N, Haber JE. (2009) Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism.. Curr Biol. 23;20(4):328-32.

Doksani Y, Bermejo R, Fiorani S, Haber JE, Foiani M. (2009) Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation. Cell. 17;137(2):247-58.

Jain S, Sugawara N, Lydeard J, Vaze M, Tanguy Le Gac N, Haber JE. (2009) A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair. Genes Dev. 1;23(3):291-303.

Kim JA, Haber JE. (2009) Chromatin assembly factors Asf1 and CAF-1 have overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete. Proc Natl Acad Sci U S A. 106(4):1151-6.


Prakash R, Satory D, Dray E, Papusha A, Scheller J, Kramer W, Krejci L, Klein H, Haber JE, Sung P, Ira G. (2008) Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Genes Dev. 1;23(1):67-79.

Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V. (2009) Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity. EMBO J. 23;27(14):1953-62..

Coïc E, Feldman T, Landman AS, Haber JE. (2008) Mechanisms of Rad52-independent spontaneous and UV-induced mitotic recombination in Saccharomyces cerevisiae. Genetics. 179(1):199-211.

Lazzaro F, Sapountzi V, Granata M, Pellicioli A, Vaze M, Haber JE, Plevani P, Lydall D, Muzi-Falconi M. (2008) Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. EMBO J. 27(10):1502-12.

Kim HS, Vijayakumar S, Reger M, Harrison JC, Haber JE, Weil C, Petrini JH. (2008) Functional interactions between Sae2 and the Mre11 complex.
Genetics. 178(2):711-23.

Haber JE. (2008) Alternative endings. Proc Natl Acad Sci U S A. 105(2):405-6.


De Koning L, Corpet A, Haber JE, Almouzni G. (2007) Histone chaperones: an escort network regulating histone traffic. Nat Struct Mol Biol. 14(11):997-1007.

Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. (2007) Mec1/Tel1 Phosphorylation of the INO80 Chromatin Remodeling Complex Influences DNA Damage Checkpoint Responses. Cell. 130(3):499-511.

Lydeard JR, Jain S, Yamaguchi M, Haber JE. (2007) Break-induced replication and telomerase-independent telomere maintenance require Pol32. Nature. 448(7155):820-3.

Flott S, Alabert C, Toh GW, Toth R, Sugawara N, Campbell DG, Haber JE, Pasero P, Rouse J. (2007) Mol Cell Biol. Jul 16

Kim JA, Kruhlak M, Dotiwala F, Nussenzweig A, Haber JE. (2007) J Cell Biol. 178(2):209-18.

Dotiwala F, Haase J, Arbel-Eden A, Bloom K, Haber JE. (2007) The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage. Proc Natl Acad Sci U S A. 104(27):11358-63.

Cortes-Ledesma F, de Piccoli G, Haber JE, Aragon L, Aguilera A. (2007) SMC proteins, new players in the maintenance of genomic stability. Cell Cycle. 6(8):914-8.

Torres-Rosell J, De Piccoli G, Cordon-Preciado V, Farmer S, Jarmuz A, Machin
F, Pasero P, Lisby M, Haber JE, Aragon L. Anaphase onset before complete DNA replication with intact checkpoint responses. (2007) Science. 315(5817):1411-5.


Ira G, Satory D, Haber JE. (2006) Conservative inheritance of newly synthesized DNA in double-strand break-induced gene conversion. Mol Cell Biol. 26(24):9424-9.

De Piccoli G, Cortes-Ledesma F, Ira G, Torres-Rosell J, Uhle S, Farmer S, Hwang JY, Machin F, Ceschia A, McAleenan A, Cordon-Preciado V, Clemente-Blanco A, Vilella-Mitjana F, Ullal P, Jarmuz A, Leitao B, Bressan D, Dotiwala F, Papusha A,
Zhao X, Myung K, Haber JE, Aguilera A, Aragon L. (2006) Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination. Nat Cell Biol. 8(9):1032-4.

Coic E, Sun K, Wu C, Haber JE. (2006) Cell cycle-dependent regulation of Saccharomyces cerevisiae donor preference during mating-type switching by SBF (Swi4/Swi6) and Fkh1. Mol Cell Biol. 26(14):5470-80

Sugawara N, Haber JE. (2006) Repair of DNA double strand breaks: in vivo biochemistry. Methods Enzymol. 408:416-29.

Valencia-Burton M, Oki M, Johnson J, Seier TA, Kamakaka R, Haber JE. (2006) Different mating-type-regulated genes affect the DNA repair defects of Saccharomyces RAD51, RAD52 and RAD55 mutants. Genetics. 174(1):41-55.

Coic E, Richard GF, Haber JE. (2006) Saccharomyces cerevisiae donor preference during mating-type switching is dependent on chromosome architecture and organization. Genetics. 173(3):1197-206.

Eachern MJ, Haber JE. (2006) Break-induced replication and recombinational telomere elongation in yeast. Annu Rev Biochem. 75:111-35

Haber JE, Debatisse M. (2006) Gene amplification: yeast takes a turn. Cell. 125(7):1237-40.

Haber JE. Transpositions and translocations induced by site-specific double-strand breaks in budding yeast. (2006) DNA Repair (Amst). 2006 Sep 8;5(9-10):998-1009.

Harrison JC, Haber JE. (2006) Surviving the breakup: the DNA damage checkpoint. Annu Rev Genet. 40:209-35

Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE,
Durocher D, Greenblatt JF, Krogan NJ. (2006) A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature. 439(7075):497-501.

Corda Y, Lee SE, Guillot S, Walther A, Sollier J, Arbel-Eden A, Haber JE, Geli V. (2005) Inactivation of Ku-mediated end joining suppresses mec1Delta lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex. Mol Cell Biol. 25(23):10652-64.


Clatworthy, AE, Valencia-Burton, MA, Haber, JE, and Oettinger, MA. (2005). The MRE11-RAD50-XRS2 complex, in addition to other non-homologous end-joining factors, is required for V(D)J joining in yeast. J Biol Chem 280, 20247-52.

Liberi, G, Maffioletti, G, Lucca, C, Chiolo, I, Baryshnikova, A, Cotta-Ramusino, C, Lopes, M, Pellicioli, A, Haber, JE, and Foiani, M. (2005). Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev 19, 339-50.

Malkova, A, Naylor, ML, Yamaguchi, M, Ira, G, and Haber, JE. (2005). RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion. Mol Cell Biol 25, 933-44.


Unal, E, Arbel-Eden, A, Sattler, U, Shroff, R, Lichten, M, Haber, JE, and Koshland, D. (2004). DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell 16, 991-1002.

Morrison, AJ, Highland, J, Krogan, NJ, Arbel-Eden, A, Greenblatt, JF, Haber, JE, and Shen, X. (2004). INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119, 767-75.

Kaye, JA, Melo, JA, Cheung, SK, Vaze, MB, Haber, JE, and Toczyski, DP. (2004). DNA breaks promote genomic instability by impeding proper chromosome segregation. Curr Biol 14, 2096-106.

Haber, JE. (2004). Telomeres thrown for a loop. Mol Cell 16, 502-3.

Haber JE, Ira G, Malkova A, Sugawara N (2004) Repairing a double-strand chromosome break by homologous recombination: revisiting Robin Holliday's model. Philos Trans R Soc Lond B Biol Sci. 359(1441):79-86.

Ira, G, Pellicioli, A, Balijja, A, Wang, X, Fiorani, S, Carotenuto, W, Liberi, G, Bressan, D, Wan, L, Hollingsworth, NM, Haber, JE, and Foiani, M. (2004). DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 431, 1011-7.

Shroff, R, Arbel-Eden, A, Pilch, D, Ira, G, Bonner, WM, Petrini, JH, Haber, JE, and Lichten, M. (2004). Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol 14, 1703-11.

Malkova, A, Swanson, J, German, M, McCusker, JH, Housworth, EA, Stahl, FW, and Haber, JE. (2004). Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII. Genetics 168, 49-63.

Wang, X, Ira, G, Tercero, JA, Holmes, AM, Diffley, JF, and Haber, JE. (2004). Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol 24, 6891-9.

Sugawara, N, Goldfarb, T, Studamire, B, Alani, E, and Haber, JE. (2004). Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1. Proc Natl Acad Sci U S A 101, 9315-20.

Miyazaki T, Bressan DA, Shinohara M, Haber JE, Shinohara A. (2004) In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair.
EMBO J. 23(4):939-49.

Bressan DA, Vazquez J, Haber JE. (2004) Mating type-dependent constraints on the mobility of the left arm of yeast chromosome III.
J Cell Biol. 164(3):361-71.

Wang X, Haber JE. (2004) Role of Saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair. PLoS Biol. 2(1):E21

Yu J, Marshall K, Yamaguchi M, Haber JE, Weil CF. (2004) Microhomology-dependent end joining and repair of transposon-induced DNA hairpins by host factors in Saccharomyces cerevisiae. Mol Cell Biol. 24(3):1351-64.


Haber JE (2003) Aging: the sins of the parents. Curr Biol. Oct 28;13(21):R843-5.

Ira G, Malkova A, Liberi G, Foiani M, Haber JE (2003) Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell. 115(4):401-11.

Lee SE, Pellicioli A, Vaze MB, Sugawara N, Malkova A, Foiani M, Haber JE. (2003)Yeast Rad52 and Rad51 recombination proteins define a second pathway DNA damage assessment in response to a single double-strand break. Mol Cell Biol. 23(23):8913-23.

Ma JL, Kim EM, Haber JE, Lee SE (2003) Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol Cell Biol. 23(23):8820-8.

Clatworthy AE, Valencia MA, Haber JE, Oettinger MA. (2003) V(D)J recombination and RAG-mediated transposition in yeast. Mol Cell. 12(2):489-99.

Sugawara N, Wang X, Haber JE. (2003). In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination. Mol Cell. 12(1):209-19.

Leroy C, Lee SE, Vaze MB, Ochsenbien F, Guerois R, Haber JE, Marsolier-Kergoat MC. (2003). PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break. Mol Cell. 11(3):827-35., Mol Cell. 11(40):1119.


Haber JE. (2002). Switching of Saccharomyces cerevisiae Mating-Type Genes. Mobile DNA II. N. Craig. ASM Press, Washington DC, pp. 927-952.

Lee SE, Bressan DA, Petrini JH, Haber JE. (2002). Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenance. DNA Repair (Amst). 1(1):27-40.

Vaze M, Pellicioli A, Lee S, Ira G, Liberi G, Arbel-Eden A, Foiani M, Haber J. (2002). Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase. Mol Cell. 10(2):373.

Ira G, Haber JE. (2002). Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol Cell Biol. 22(18):6384-92.

Sun K, Coic E, Zhou Z, Durrens P, Haber JE. (2002). Saccharomyces forkhead protein Fkh1 regulates donor preference during mating-type switching through the recombination enhancer. 16(16):2085-96


Valencia M, Bentele M, Vaze MB, Herrmann G, Kraus E, Lee SE, Schar P, Haber JE. (2001). NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature. 414(6864):666-669.

Haber JE. (2001). Uses and abuses of HO endonuclease. Methods Enzymol. 350:141-64.

Haber JE, Heyer WD. (2001). The Fuss about Mus81. Cell. 107(5):551-4.

Haber JE. Hypermutation: give us a break. (2001). Nat Immunol. 2(10):902-3.

Lee SE, Pellicioli A, Malkova A, Foiani M, Haber JE. (2001). The Saccharomyces recombination protein Tid1p is required for adaptation from G2/M arrest induced by a double-strand break. Curr Biol. 11(13):1053-7.

Kraus E, Leung WY, Haber JE. (2001). Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A. 98(15):8255-62.

Zhou Z, Sun K, Lipstein EA, Haber JE. (2001). A Saccharomyces servazzii clone homologous to Saccharomyces cerevisiae chromosome III spanning KAR4, ARS 304 and SPB1 lacks the recombination enhancer but contains an unknown ORF. Yeast. 18(9):789-95.

Paques F, Richard GF, Haber JE. (2001). Expansions and contractions in 36-bp minisatellites by gene conversion in yeast. Genetics. 158(1):155-66.

Malkova A, Signon L, Schaefer CB, Naylor ML, Theis JF, Newlon CS, Haber JE. (2001). RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Genes Dev. 15(9):1055-60.

Pellicioli A, Lee SE, Lucca C, Foiani M, Haber JE. (2001). Regulation of saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol Cell. 7(2):293-300.

Signon L, Malkova A, Naylor ML, Klein H, Haber JE. (2001). Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol Cell. Biol. 21(6):2048-56.


Haber, J. E. (2000). Lucky breaks: analysis of recombination in Saccharomyces. Mutat Res. 451(1-2): 53-69.

Haber, J. E. (2000). Partners and pathways repairing a double-strand break. Trends Genet. 16(6): 259-64.

Haber, J. E. (2000). Recombination: a frank view of exchanges and vice versa. Curr Opin Cell Biol. 12(3): 286-92.

Lee SE, Pellicioli A, Demeter J, Vaze MP, Gasch AP, Malkova A, Brown PO, Botstein D, Stearns T, Foiani M, Haber JE (2000) Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae Cold Spring Harb Symp Quant Biol. ;65:303-14

Malkova A, Klein F, Leung WY, Haber JE. (2000). HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events. Proc. Natl. Acad. Sci. U S A. Dec 19;97(26):14500-14505.

Lee SE, Pellicioli A, Demeter J, Vaze MP, Gasch AP, Malkova A, Brown PO, Botstein D, Stearns T, Foiani M, Haber JE. (2000). Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae.
Cold Spring Harb Symp Quant Biol. 65:303-14.

Demeter, J., Lee, S. E., Haber, J. E. and Stearns, T. (2000). The DNA damage checkpoint signal in budding yeast is nuclear limited. Mol Cell. 6(2): 487-92.

Evans, E., Sugawara, N., Haber, J. E. and Alani, E. (2000). The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo. Mol Cell. 5(5): 789-99.

Richard, G. F., Goellner, G. M., McMurray, C. T. and Haber, J. E. (2000). Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex. Embo J. 19(10): 2381-90.

Sugawara, N., Ira, G. and Haber, J. E. (2000). DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol. 20(14): 5300-9.


Colaiacovo, M. P., Paques, F. and Haber, J. E. (1999). Removal of one nonhomologous DNA end during gene conversion by a RAD1- and MSH2-independent pathway. Genetics. 151(4): 1409-23.

Haber, J. E. (1999). DNA recombination: the replication connection. Trends Biochem Sci. 24(7): 271-5.

Haber, J. E. (1999). DNA repair. Gatekeepers of recombination. Nature. 398(6729): 665, 667.

Haber, J. E. (1999). Sir-Ku-itous routes to make ends meet. Cell. 97(7): 829-32.

Holmes, A. and Haber, J. E. (1999). Physical monitoring of HO-induced homologous recombination. Methods Mol Biol. 113: 403-15.

Holmes, A. M. and Haber, J. E. (1999). Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell. 96(3): 415-24.

Le, S., Moore, J. K., Haber, J. E. and Greider, C. W. (1999). RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics. 152(1): 143-52.

Lee, S. E., Paques, F., Sylvan, J. and Haber, J. E. (1999). Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr Biol. 9(14): 767-70.

Paques, F. and Haber, J. E. (1999). Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 63(2): 349-404

Richard, G. F., Dujon, B. and Haber, J. E. (1999). Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats. Mol Gen Genet. 261(4-5): 871-82.

Studamire, B., Price, G., Sugawara, N., Haber, J. E. and Alani, E. (1999). Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination. Mol Cell Biol. 19(11): 7558-67.


Bosco, G. and Haber, J. E. (1998). Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics. 150(3): 1037-47.

Haber, J. E. (1998). Meiosis. Searching for a partner. Science. 279(5352): 823-4.

Haber, J. E. (1998). The many interfaces of Mre11. Cell. 95(5): 583-6.

Haber, J. E. (1998). A locus control region regulates yeast recombination. Trends Genet. 14(8): 317-21.

Haber, J. E. (1998). Meiosis: Avoiding inappropriate relationships. Curr Biol. 8(23): R832-5.

Haber, J. E. (1998). Mating-type gene switching in Saccharomyces cerevisiae. Annu Rev Genet. 32: 561-99.

Haber, J. E. and Louis, E. J. (1998). Minisatellite origins in yeast and humans. Genomics. 48(1): 132-5.

Lee, S. E., Moore, J. K., Holmes, A., Umezu, K., Kolodner, R. D. and Haber, J. E. (1998). Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell. 94(3): 399-409.

Nugent, C. I., Bosco, G., Ross, L. O., Evans, S. K., Salinger, A. P., Moore, J. K., Haber, J. E. and Lundblad, V. (1998). Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr Biol. 8(11): 657-60.

Paques, F., Leung, W. Y. and Haber, J. E. (1998). Expansions and contractions in a tandem repeat induced by double-strand break repair. Mol Cell Biol. 18(4): 2045-54.

Umezu, K., Sugawara, N., Chen, C., Haber, J. E. and Kolodner, R. D. (1998). Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics. 148(3): 989-1005.

Wu, C., Weiss, K., Yang, C., Harris, M. A., Tye, B. K., Newlon, C. S., Simpson, R. T. and Haber, J. E. (1998). Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching. Genes Dev. 12(11): 1726-37.