Current Members News


Post-Doctoral Fellow

2017 - PhD Chemical Engineering, University of Minnesota, USA
2011 - BS, Chemical Engineering (Minor: Mathematics), Michigan Technological University

Email: woldring @
Office: Volen 443
Dept. of Biochemistry, MS 009
Brandeis University
415 South Street
Waltham, MA 02454, USA
Phone (Lab): (781) 736-2326

Daniel R. Woldring

Research Interests

I use high-throughput approaches to discover novel protein function and explore protein evolution.


DR Woldring, PV Holec, LA Stern, Y Du, BJ Hackel: “Sitewise Diversity to Optimize Evolutionary Fitness of a Three-helix Bundle Combinatorial Library" Biochemistry (2017) 55(11):1656-1671

LA Stern, CM Csizmar, DR Woldring, CR Wagner, BJ Hackel: “Titratable Avidity Reduction Enhances Affinity Discrimination in Cell Selections of Yeast-Display Ligands” ACS Comb Sci (2017)

MA Kruziki, BA Case, JY Chan, EJ Zudock, DR Woldring, D Yee, BJ Hackel: “A 64Cu-labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor.” Molecular Pharma (2016) 13(11)

DR Woldring, PV Holec, BJ Hackel: “ScaffoldSeq: Software for characterization of directed evolution populations” Proteins: Structure, Function and Bioinformatics (2016) 84(7):869-874

DR Woldring, PV Holec, H Zhou, BJ Hackel: “High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin Domains” PLoS One (2016) 10(9)

MA Kruziki, S Bhatnagar, DR Woldring, VD Duong, BJ Hackel: “A 45-Amino- Acid Scaffold Mined from the PDB for High-Affinity Ligand Engineering” Chemistry & Biology (2015) 22(7):946-956

BJ Hackel, H Zhou, DR Woldring: “Compositions and Methods that Involve Protein Scaffolds that Specifically Bind to Hepatocyte Growth Factor Receptor.” US Patent App 15/198,839 (June 30 2016)