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PhD Candidate in Biochemistry


Education
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Contact
Email: jstiller @ brandeis.edu
Office: Volen 443
Dept. of Biochemistry, MS 009
Brandeis University
415 South Street
Waltham, MA 02454, USA
Phone (Lab): (781) 736-2326

John Stiller


Research Interests

Protein’s exist upon a delicate energy landscape where multiple states are within several kJ of one another. While current structural techniques characterize the lowest energy conformation, the higher energy states remain obscured. However, recently NMR techniques have been developed which allows one to infer structural information about these excited states. With that in mind, my interests involve structurally investigating protein ensembles and discovering how regulation and drug binding are manipulated by conformational interexchange.


Publications

Vy Nguyen*, Christopher Wilson*, Marc Hoemberger, John B. Stiller, Roman Agafonov, Steffen Kutter, Justin English, Douglas Theobald, Dorothee Kern Evolutionary drivers of thermoadaptation in enzyme catalysis. Science (2017) 355(6322):289-294