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Post-Doctoral Fellow


Education
2004 - Diploma Biochemistry, Martin-Luther-Universität Halle-Wittenberg, Institut für Biochemie und Biotechnologie, Germany
2009 - PhD Biochemistry, Martin-Luther-Universität Halle-Wittenberg, Institut für Biochemie und Biotechnologie, Germany

Contact
Email: steffen @ brandeis.edu
Office: Volen 443
Dept. of Biochemistry, MS 009
Brandeis University
415 South Street
Waltham, MA 02454, USA
Phone (Lab): (781) 736-2326
Website:Personal Webpage

Steffen Kutter


Research Interests

I'm interested in structure function relationships by using a wide range of methods.


Professional Experience

Expression and purification of proteins; enzyme kinetic measurements and data examination; UV/VIS spectroscopy; small angle X-ray solution scattering measurement and data analysis (Atsas package); protein crystallization, data collection, processing, refinement, and model building (imosflm, CCP4-suite, Wincoot).


Publications

Vy Nguyen*, Christopher Wilson*, Marc Hoemberger, John B. Stiller, Roman Agafonov, Steffen Kutter, Justin English, Douglas Theobald, Dorothee Kern Evolutionary drivers of thermoadaptation in enzyme catalysis. Science (2017) 355(6322):289-294

Kutter, S., Wille, G., Relle, S., Weiss, M. S., Hübner, G.and König, S. "The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis. Implications for the substrate activation mechanism of this enzyme." FEBS J. (2006) 273:4199-4209.

Kutter, S., Spinka, M., Koch, M. H. J. and König, S. "The influence of protein concentration on oligomer structure and catalytic function of two pyruvate decarboxylases." Protein J. (2007) 26:585-591.

Kutter, S., Weiss, M. S., Wille, G., Golbik, R., Spinka, M. and König, S. "Covalently bound substrate at the regulatory site triggers allosteric enzyme activation." J. Biol. Chem. (2009) 284:12136-12144.

König, S., Spinka, M.and Kutter, S. "Allosteric activation of pyruvate decarboxylases. A never-ending story." J. Mol. Catal. B (2009) 61:100-110.

Publication List on PubMed