The Quantal Response:

Monte-Carlo simulations show that the quantal response is generated by AMPA channels in a "hotspot" of 200 mm diameter, a result that has important implications for transmission and LTP. Properties of quantal transmission at CA1 synapses. Raghavachari S, Lisman JE. J Neurophysiol. 2004 Oct;92(4):2456-67. Epub 2004 Apr 28. [ PDF ] A unified model of the presynaptic and postsynaptic changes during LTP at CA1 synapses. Lisman J, Raghavachari S.Sci STKE. 2006 Oct 10;2006(356): re11. [ PDF ]