Seminars

Upcoming Seminars / Seminars This Week

Thu 3/23/17 12 noonRosenstiel 118
Psychology Department Brown Bag
Brandon Hager (Social Interaction & Motivation Lab)
Is the Human Mirror System Complex and Adaptive?
Nadya Greenberg (Social Interaction & Motivation Lab)
Competence and Warmth Relate to Motor Resonance

Thu 3/23/17 2 pmGoldsmith 317
Everytopic Seminar
Xin Sun (MIT)
Liouville quantum gravity and peanosphere
Hosted by Prof. Konstantin Matveev

Thu 3/23/17 4 pmAbelson 229
MRSEC: Biological Active Materials (IRG2)
Greg Hoeprich and Guillaume Duclos (Brandeis)
Disordered actomyosin networks are sufficient to produce cooperative and telescopic contractility
Pizza will be serve at 5:30.
Hosted by Gregory Hoeprich

Thu 3/23/17 4:30 pmGoldsmith 317
Joint Mathematics Colloquium
Richard Kenyon (Brown University)
Linear spaces of tilings
Statistical mechanics deals with measures in high dimensions. Basically there are only three situations where we can deal effectively with such measures: when the measure is a product measure; when it is Gaussian; or when it is determinantal. The third case is the least familiar. We discuss a model of tilings in the plane with convex polygonal tiles, related to a determinantal measure. One main result, roughly stated, is "choose your favorite shape for each tile (up to scale, and subject to the constraint that adjacent tiles have their common edges in the same direction), then there is a tiling with those shapes".

Refreshments at 4pm, Goldsmith 100
Hosted by Prof. An Huang

Fri 3/24/17 10 amVolen 101
Computer Science Seminar (Machine Learning & Data Science Series)
Minwoo "Jake" Lee (Computer Science Dept. Colorado State University)
Sparse Bayesian Reinforcement for Robust and Efficient Learning
Abstract: An intelligent agent often fails to learn when it encounters a new environment because it forgets what it has learned. This impacts the stability of learning process. One instance of this is well-known "catastrophic forgetting" of neural networks. Biased input data used for neural network training cause the networks to lose the learned knowledge as new data arrive from outside the old data space. To overcome this, sparse Bayesian reinforcement learning proposes a way to gradually gain knowledge about the domain with a sparse learning model for efficiency. Robust learning can be achieved through a knowledge augmentation framework. With the proposed heuristics, we claim that the sparsity of the domain is maintained. The Bayesian model makes learning more efficient by providing a way to make a correct decision depending on the confidence of estimation. The proposed framework has been successfully applied to analytical learning and efficient search for transfer learning and efficient fine control. This will be demonstrated in application to control of a simulated octopus arm.

Speaker Bio: Minwoo Lee is a PhD candidate in Computer Science at Colorado State University. He received his M.S. and B.S. from Korea Aviation University in 2002. His research interests focus on machine learning, with, emphasis on reinforcement learning, transfer learning, sparse learning, multiagent learning, fine control based policy development, knowledge representation and robust knowledge augmentation. He received REUSSIINSF fiends for research with Imia, France in 2012 and investigated robust high dimensional clustering models for biomedical data. His recent research about pretraining deep networks for reinforcement learning agents received the best paper award from IJCNN 2015. He has served as a referee for journals such as IEEE Transactions on Neural Networks and Learning Systems (TNNLS) and conferences such as IEEE Conference of Decision and Control (CDC), IEEE International Joint Conference on Neural Networks (IJCNN), and IEEE International Conference on Tools with. Artificial Intelligence (ICTAI).

Refreshments will be served.

Fri 3/24/17 11 amAbelson 131
Chemistry Seminar (Inorganic/Organic Seminar)
Hongtu Zhang (Grad Student Brandeis Chemistry Department)
Photocatalytic splitting of water and CO2

Fri 3/24/17 11:15 amRosenstiel 118
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
Myles Akabas, M.D., Ph.D. (Albert Einstein College of Medicine)
Malaria Purine Transporter: Novel Target for Development of New Antimalarial Drugs
Hosted by Chris Miller

Fri 3/24/17 12:30 pmGerstenzang 123
Molecular and Cell Biology & Neuroscience Student Seminars
Brenda Lemos (Haber Lab)
Chelsea Groves Kuhnle (VanHooser/Turrigiano Labs)

Mon 3/27/17 11 amVolen 201
Computational Neuroscience Journal Club
Leandro Alonso (Rockefeller University)
Criticality in neural dynamics
Pizza to follow
Hosted by Paul Miller

Mon 3/27/17 11 amAbelson 307
String Theory Seminar
Harsha Hamapapura (Brandeis University)
The Large N Limit of the O(N) Model
Hosted by Albion Lawrence

Mon 3/27/17 12 noonRosenstiel 118
Molecular Genetics Journal Club
Sebastian Kadener (Brandeis University)
Rounding up the circle, unraveling molecular and physiological functions of circRNAs
Hosted by Avi Rodal

Mon 3/27/17 1 pmGoldsmith 226
Dynamics and Number Theory
Avraham Bourla (Brandeis)
The Ostrowski Expansions Revealed
Hosted by Prof. Dmitry Kleinbock

Mon 3/27/17 4 pmGerstenzang 121
Chemistry Department Colloquium
Gang Han (University of Mass. Medical School, Worcester)
Small and Bright: Tailoring Luminescent Nanoparticles in Biology
Hosted by Bing Xu

Tue 3/28/17 12:30 pmGerstenzang 121
M.R. Bauer Distinguished Guest Lecture Series
Casper Hoogenraad (Utrecht University)
Cytoskeleton-based mechanisms underlying the biology and diseases of the nervous system
Hosted by Avital Rodal and Suzanne Paradis

Tue 3/28/17 2 pmGoldsmith 317
Topology Seminar
Devin Murray (Brandeis)
The Curve Complex and Hierarchies
Hosted by Prof. Ruth Charney

Tue 3/28/17 3:30 pmGerstenzang 122
Physical Chemistry Seminar
Zhaoqianqi Feng (Grad Student Brandeis Chemistry Dept.)
Stimuli-Responsive Nanocarriers for Drug Delivery
Hosted by Casey Wade

Tue 3/28/17 4 pmAbelson 131
Physics Department Colloquium (Joint Quantitative Biology-Physics Department Colloquium)
Steve Harvey (University of Pennsylvania, School of Medicine)
Physics explains how a virus motor stuffs a long DNA into a small shell
Many viruses that infect bacteria (bacteriophages) have similar structures: an icosahedral shell (the capsid) surrounding the double-stranded DNA genome (dsDNA), and a tail structure designed to recognize the target bacterium, penetrate the bacterial cell wall, and deliver the DNA into the bacterial cell through a channel in the tail.

The assembly of a new virus has three steps: (1) the capsid assembles spontaneously, nucleated by a protein complex (the motor) at one vertex of the icosahedron; (2) the motor captures dsDNA and drives it into the empty capsid, using the energy of ATP hydrolysis to overcome the strong electrostatic forces that resist DNA confinement; and (3) the tail assembly replaces one of the motor's components, forming the mature virus.

We are investigating the second step, asking how the motor drives the DNA into the capsid. Many models have been proposed, most based on the belief that DNA is passive substrate, gripped by the motor and propelled forward with lever-like motions. I have proposed that DNA is an active component of force generation. In the original "scrunchworm" model (1), the DNA is driven cyclically between the standard A-DNA and B-DNA conformations. A-DNA is shorter than B-DNA, and the cycle of DNA shortening and lengthening is coupled to a protein-DNA grip-and-release cycle that rectifies the motion, generating DNA translocation. Our first computer simulations on DNA within the channel of a viral portal complex provided some support for this model (2).

We have now completed simulations on DNA-portal interactions in four different complexes. Those simulations have confirmed the role of the DNA shortening and lengthening motions. But they also show that the proposed mechanism, based on transitions between A-DNA and B-DNA, is not correct. Instead, the DNA conformational changes are the consequence of a surprisingly simple physical mechanism (3).

This talk is the first public presentation of these results.

(1) SC Harvey (2015), J Struct Biol 189:1-8.

(2) JT Waters, HD Kim, JC Gumbart, X-J Lu, and SC Harvey (2016), J Phys Chem B 120:6200-6207.

(3) KS Sharp, SC Harvey, et al. (manuscript in preparation)

Refreshments at 3:30 outside Abelson 131
Hosted by Michael Hagan

Wed 3/29/17 12 noonRosenstiel 118
Neurobiology Journal Club (M.R. Bauer Distinguished Guest Lecture)
Casper Hoogenraad (Utrecht University)
Monitoring and manipulating neuronal cargo transport
Hosted by Avi Rodal

Thu 3/30/17 11 amGoldsmith 117
Thesis Seminar (Graduate Program in Mathematics)
Nick Wadleigh (Brandeis)
Shrinking Target Phenomena Applied to Zero-One Laws for Uniform Diophantine Approximation
Hosted by Math Department

Thu 3/30/17 12 noonRosenstiel 118
Psychology Department Brown Bag
William Goodman (Health Lab)
TBA
Claire Elling (Health Lab)
TBA

Thu 3/30/17 2 pmAbelson 229
Theory IGERT Seminar
Walter Fontana (Harvard Medical School)
Replacing a world we don’t understand with a model we don’t understand
Simplifying somewaht, we might say that, in physics, understanding precedes modeling. In molecular systems biology, as we get to know more about the inner workings of cells at the molecular scale, it appears as if modeling may have to precede understanding (at least initially). A model then must become a formal and executable representation of the facts it is based upon. I will sketch a rule-based approach of this vision that is aimed at reasoning about systems of protein-protein interaction. My intent is to spend most of the time on the opportunity, but also the challenge, of reasoning about causality in such models.
Hosted by Prof. Albion Lawrence

Thu 3/30/17 4 pmAbelson 229
MRSEC: Membrane-based Materials (IRG1)
Rylie Walsh and Joanna Robaszewski (Brandeis)
Amphipathic DNA origami nanoparticles to scaffold and deform lipid membrane vesicles by Aleksander Czogalla, Dominik J. Kauert, Henri G. Franquelim, Veska Uzunova, Yixin Zhang, Ralf Seidel, and Petra Schwille
Pizza will be served from 5:00-5:30
Hosted by Masha Siavashpouri

Fri 3/31/17 11:15 amRosenstiel 118
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
Brian Kelch (UMass Medical School)
Macromolecular machines on DNA: motors, rings, springs and things
Hosted by Timo Street

Fri 3/31/17 12:30 pmGerstenzang 123
Molecular and Cell Biology & Neuroscience Student Seminars
Mike Hobin (Griffith Lab)
Linnea Herzog (Katz/Jadhav Labs)

Fri 3/31/17 1 pmRosenstiel 118
Thesis Seminar (Graduate Program in Biochemistry and Biophysics)
Patrick McCarthy
Reversibly Constraining the UI snRNP to a pre-mRNA via an Engineered Site-Specific Disulfide Bond

Fri 3/31/17 4 pmGoldsmith 300
Thesis Seminar (Graduate Program in Mathematics)
Yiting Li (Brandeis)
Rigidity of Eigenvalues for Beta Ensemble in Multi-Cut Regime
Hosted by Math Department

Tue 4/4/17 12:30 pmGerstenzang 121
Joint Biology/Neuroscience Colloquium
Torben Heick-Jensen (Aarhus University)
Transcription and RNA processing

Tue 4/4/17 4 pmAbelson 131
Physics Department Colloquium
Amala Mahadevan (Woods Hole Oceanographic Institution)
Cookies and Coffee to be served outside Abelson 131 at 3:30
Hosted by Albion Lawrence

Wed 4/5/17 12 noonRosenstiel 118
Neurobiology Journal Club
Matthias Schlichting (Rosbash Lab)
Intra-neuronal Competition for Synaptic Partners Conserves the Amount of Dendritic Building Material
Ref: http://dx.doi.org/10.1016/j.neuron.2016.12.043
Madelen Diaz (Rosbash Lab)
Neurotoxic reactive astrocytes are induced by activated microglia
Ref: http://www.nature.com/nature/journal/v541/n7638/full/nature21029.html#ref5

Wed 4/5/17 12 noonLown 201
Dissertation Defense
Ashley Geiger (Health Lab, Brandeis University)
Expanding subjective social status across social networks: Links between perceived social standing and mental health
Existing literature has identified a gradient relationship between social status and health such that it is not only the lowest levels of status that are linked with poorer health; but instead, each step down in status is associated with incremental increases in health risks. Increasingly, research has highlighted role of subjective perceptions of social status and their contribution to mental health beyond objective status information such as income or education. This project expands existing measures of subjective social status (status in the nation and community) to understand how social standing in closer, more narrowly defined social groups (neighborhood, friends, and family) is linked to mental health. Specifically, I will present findings on how subjective social status ratings relative to these five social networks are linked with depressive symptoms in different socioeconomic contexts (i.e., unemployment) and longitudinally over the course of a health improvement intervention.
Hosted by Jutta Wolf

Thu 4/6/17 12 noonRosenstiel 118
Psychology Department Brown Bag
Dan Levin (Aging, Culture & Cognition Lab)
TBA
Yile Sun (Vision Lab)
TBA

Thu 4/6/17 4 pmAbelson 229
MRSEC Seminar
Dan Beller (Harvard)
Free pizza will be served from 5:00-5:30
Hosted by Baptiste Blanc

Thu 4/6/17 4:30 pmGoldsmith 317
Joint Mathematics Colloquium
Sergey Lando (Skolkovo Institute of Science and Technology (visiting MIT))
Combinatorial solutions to integrable hierarchies
In 2000, answering a question by R. Pandharipande, A. Okoun'kov proved that a generating function for connected double Hurwitz numbers satisfies Toda equations. Since then, a number of other solutions to integrable hierarchies, whose coefficients are answers to various enumerative problems, has been constructed in the work of I. Goulden, D. Jackson, J. Harnad, P. Zograf, and others. The talk will present a review of modern approaches to constructing such formal solutions. The relationship between these approaches and combinatorics of symmetric groups and their representations will be explained. Applications of the results to constructing efficient computations in enumeration of various kinds of maps will be given.
Refreshments at 4pm in Goldsmith 100
Hosted by Prof. An Huang

Fri 4/7/17 11 amAbelson 131
Chemistry Seminar (Inorganic/Organic Seminar)
Andrew Poitras (Grad Student Brandeis Chemistry Department)
O2 Reduction by first row transition metals

Fri 4/7/17 11:15 amRosenstiel 118
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
John Kuriyan (UC Berkeley)
Evolutionary conservation and oncogenic potential of Ras analyzed by saturation mutagenesis
Hosted by Doro Kern

Fri 4/7/17 12:30 pmGerstenzang 123
Molecular and Cell Biology & Neuroscience Student Seminars
Chloe Greppi (Garrity Lab)
Dave Hampton (Marder Lab)

Tue 4/11/17 3:30 pmGerstenzang 122
Physical Chemistry Seminar
Xinyue Liu (Grad Student Chemistry Department)
TBA
Hosted by Casey Wade

Tue 4/11/17 4 pm
Physics Department Colloquium
No colloquium (Passover and Spring Recess)

Wed 4/12/17 1 pmVolen 201
Safety Training
Andrew Finn (Environmental Health & Safety)
Empty Container Handling

Fri 4/14/17 11:15 amRosenstiel 118
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
Luke Chao (Department of Molecular Biology Simches Research Center, MGH)
Single particle kinetic and electron cryo-microscopy studies of flavivirus membrane fusion
Hosted by Tijana Ivanovic

Fri 4/14/17 11:15 amRosenstiel 118
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
Luke Chao (Massachusetts General Hospital)
Hosted by Tijana Ivanovic

Fri 4/14/17 12:30 pmGerstenzang 123
Molecular and Cell Biology & Neuroscience Student Seminars
NO PIZZA TALKS - March Recess, Passover, Good Friday

Tue 4/18/17 4 pm
Physics Department Colloquium
No colloquium (Passover and Spring Recess)
TBA

Wed 4/19/17 12 noonRosenstiel 118
Neurobiology Journal Club
Erin A. Clark (Nelson Lab)
TBA
Sara Haddad (Marder Lab)
TBA

Wed 4/19/17 4 pmGerstenzang 121
Chemistry Department Colloquium
Kristie Koski (University of California, Davis)
2D Materials: From Innovative Chemistry to Novel Applications
This is a Brandeis Monday
Hosted by Casey Wade

Thu 4/20/17 11:15 amShapiro Science Center GL14
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
Senior Students (Brandeis University)
Senior Honors Talks

Thu 4/20/17 12 noonRosenstiel 118
Psychology Department Brown Bag
Tianyou Zhou (Vision Lab)
TBA
Jeremy Simon (Social Interaction & Motivation Lab)
TBA

Thu 4/20/17 2 pmAbelson 229
Theory IGERT Seminar
Archana Kamal (UMass Lowell)
Hosted by Prof. Albion Lawrence

Fri 4/21/17 11:15 amRosenstiel 118
Biochemistry-Biophysics Friday Lunchtime Pizza Talks
Senior Students (Brandeis University)
Senior Honors Talks

Fri 4/21/17 12:30 pmGerstenzang 123
Molecular and Cell Biology & Neuroscience Student Seminars
NO PIZZA TALKS scheduled

Mon 4/24/17 4 pmGerstenzang 121
Chemistry Department Colloquium
George Makhatadze (Rennsselaer Polytech)
Man-Made versus Naturally-Evolved Protein Folding Landscapes
Hosted by Pochapsky/Ringe

 
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