Thu 10/27/16 12 noon  Rosenstiel 118 
Psychology Department Brown Bag 
Stephanie Robinson (Lifespan Lab) 
Planning the next steps: Using an implementation intention approach to increase daily walking 
Alycia Sullivan (Lifespan Lab) 
Walk to a better night of sleep: Sleep, steps, and exercise intensity 

Fri 10/28/16 11:15 am  Rosenstiel 118 
BiochemistryBiophysics Friday Lunchtime Pizza Talks 
Tarun Kapoor (The Rockefeller University) 
How nanometersized proteins build micronsized structures required for cell division 
Hosted by Chris Miller 

Fri 10/28/16 12:30 pm  Gerstenzang 123 
Molecular and Cell Biology & Neuroscience Student Seminars 
Dan Powell (Marder Lab) 
Denise Hilton (Goode Lab) 

Fri 10/28/16 2:30 pm  Abelson 229 
IRG 2 
Caleb Wagner (Baskaran/Hagan Labs Grad Student) 
Statistical mechanics of ideal active Brownian particles in 1d confinement 
The statistical mechanics of ideal active Brownian particles in 1d confinement is studied by obtaining the exact solution of the steadystate Smoluchowski equation for the 1particle distribution function. The solution is derived using results from the theory of twoway diffusion equations, combined with an iterative procedure that is justified by numerical results and plausibility arguments. The spatial distribution and orientational order of the ensemble are discussed, and scaling relations for the bulk density and the fraction of particles on the confining wall are rigorously derived. By considering a constantflux steady state, an effective diffusivity for ABPs is obtained which shows signatures of the persistent motion that characterizes ABP trajectories. Finally, we discuss how the techniques used here generalize to other active models, including systems whose activity is modeled in terms of an OrnsteinUhlenbeck process. 

Sat 10/29/16 9 am  Lemberg Academic Center 
Greater Boston Area Statistical Mechanics Meeting (GBASM) 
Greater Boston Area Statistical Mechanics Meeting 
Craig Maloney, Northeastern Bin Zhang, MIT Greg Grason, UMASS Amherst YuShan Lin, Tufts University 
Registration due by Saturday October 22nd: https://sites.google.com/a/brandeis.edu/gbasm/home 
Hosted by Professor Michael Hagan 

Mon 10/31/16 11 am  Abelson 307 
String Theory Seminar 
Netta Englehardt (Princeton) 
Into the Bulk: A Covariant Approach 

Mon 10/31/16 11 am  Volen 201 
Computational Neuroscience Journal Club 
Suman Guha 
pizza at noon 

Mon 10/31/16 12 noon  Rosenstiel 118 
Molecular Genetics Journal Club 
Fred Kramer (Public Health Research Institute Center, New Jersey Medical School  Rutgers, The State University of New Jersey) 
SuperSelective Primers for Multiplex Realtime PCR Assays that Assess the Abundance of Rare Mutations Associated with Cancer 
Hosted by Larry Wangh 

Mon 10/31/16 1 pm  Goldsmith 226 
Dynamics and Number Theory 
Nick Wadleigh (Brandeis) 
Some Dirichlettype theorems via shrinking target phenomena 
Hosted by Professor Dmitry Kleinbock 

Mon 10/31/16 4 pm  Gerstenzang 121 
Chemistry Department Colloquium 
Alan Aspuru Guzik (Harvard University) 
Billions and billions of molecules 
Hosted by Judith Herzfeld 

Tue 11/1/16 12:30 pm  Gerstenzang 121 
M.R. Bauer Distinguished Guest Lecture Series 
Huda Zoghbi (Baylor College of Medicine) 
Rett syndrome: From the clinic to genomes, epigenomes, and neural circuits 
In this lecture I will share my journey with Rett syndrome from my first patient encounter, through the challenges of watching hundreds of girls go through a sequence of normal development, regression, and then progression, and the 16 year search for the cause of this disorder till we discovered that mutations in the Xlinked methylCpGbinding protein 2 (MECP2) caused Rett syndrome. The lecture will cover studies aimed at understanding disease mechanim and the insights we learned from various animal models.Through the use of geneticallyengineered mice, we learned that the brain is acutely sensitive to the levels of MeCP2 and that both decreases and increases in MeCP2 levels (or function) can lead to neurological and beahvioral features that are also observed in humans. We also learned that the protein is needed throughout life to maintain normal neurological functions and that normalizing its levels can reverse diseaselike features in a mouse model of the human MECP2 duplication syndome. We have been gradually pinpointing the neurons that mediate various neurological and psychiatric symptoms, and more recently uncovered circuit abnormalities in both the Rett and duplication mouse models. Building on this understanding of neural substratephenotype relationships, we showed that deep brain stimulation of a specific neural network improved learning and memory in a Rett syndrome mouse model. 
Hosted by Eve Marder and Michael Rosbash 

Tue 11/1/16 1 pm  Goldsmith 226 
Combinatorics Seminar 
Ira Gessel (Brandeis University) 
An Introduction to Symmetric Functions 
This talk will be an introduction to the theory of symmetric functions, including the important bases for symmetric functions, the scalar product, connections with representations of symmetric groups, and plethysm. 
Hosted by Olivier Bernardi and Yan Zhuang 

Tue 11/1/16 2 pm  Goldsmith 300 
Topology Seminar 
Adam Levine (Princeton University) 
Concordance of knots in homology spheres 
I will discuss the concordance group of knots in homology 3spheres that bound homology 4balls, and how it relates to the traditional knot concordance group and the notion of nonlocallyflat piecewiselinear concordance. My earlier work showed that the natural map from the traditional concordance group to the extended version is not surjective; we now go further and see that the image of this map has infinite index. This is joint work with Jen Hom and Tye Lidman. 
Hosted by Prof. Daniel Ruberman 

Tue 11/1/16 4 pm  Abelson 131 
Physics Department Colloquium 
Christopher Laumann ( Boston University) 
TBA 
Refreshments at 3:30pm, outside Abelson 131 
Hosted by 

Wed 11/2/16 12 noon  Rosenstiel 118 
Neurobiology Journal Club (Bauer Distinguished Guest Lecturer) 
Huda Zoghbi ( Baylor College of Medicine) 
Rett syndrome: From the clinic to genomes, epigenomes, and neural circuits 

Wed 11/2/16 3:30 pm  Volen 101 
Computer Science Seminar 
Alex Plotnick (Research Scientist, SIFT) 
Blocks and Biology: Computational Linguistics at Work and Play 
What do the sentences "Put a block on the table" and "MEK phosphorylates ERK, which translocates to the nucleus" have in common? On the surface, not very much; one describes a physical translation of a macroscopic cube, the other a biochemical reaction between a pair of proteins in a cell. But computational linguistics is a crossdomain enterprise: given appropriate lexical definitions, neither a parser nor a generator should have any more trouble with one than the other. In this talk, I will discuss some of the issues and challenges we face in processing and representing the meaning of such disparate sentences in the context of DARPA's "Communicating with Computers" and "Big Mechanism" programs. Alex Plotnick received his Ph.D. in Computer Science from Brandeis University in the summer of 2015. Since then, he has been happily hacking away as a researcher for SIFT, working primarily on the Sparser natural language analysis system and the Mumble natural language generation system. 
Hosted by James Pustejovsky 

Thu 11/3/16 12 noon  Rosenstiel 118 
Psychology Department Brown Bag 
Drs. Don Katz and Jennifer Gutsell (Psychology Department) 
Job after Graduation 
Hosted by Xiaodong Liu 

Fri 11/4/16 11:15 am  Rosenstiel 118 
BCBP Rotation Talks 
FirstYear BCBP PhD Students 
FirstYear Biochemistry & Biophysics Doctoral Student Rotation Talks 
Rotation talks will run from 11:15am  12:30pm. 

Fri 11/4/16 12:30 pm  Gerstenzang 123 
Molecular and Cell Biology & Neuroscience Student Seminars 
Shen Wang (VanHooser Lab) 
Nikki Amichetti (Wingfield Lab) 

Mon 11/7/16 10 am  Rosenstiel 118 
Computer Science Seminar (Computational Linguistics Seminar Series) 
Patrick Hanks (Professor of Lexicography, University of Wolverhampton, UK) 
Linguistic Creativity 
The second in a series of three talks to explore how people use words to make meanings, and ask how meaning can be processed computationally. This talk explores how speakers and writers exploit phraseological norms. It proposes that language is indeed rulegoverned behavior, but that there is not just one monolithic system of rules, but rather two: the rules of grammar and rules for exploiting phraseological norms creatively. The emphasis here will be on figurative language, in particular metaphor and simile. Finally, I will discuss the function, structure, and semantics of similes and show how these are different from the function, structure, and semantics of metaphor. 
The second in a series of three talks that explore how people use words to make meanings, and ask how meaning can be processed computationally. 
Hosted by James Pustejovsky 

Mon 11/7/16 11 am  Abelson 307 
String Theory Seminar 
Cesar Agon (Brandeis) 

Hosted by Professor Matthew Headrick 

Mon 11/7/16 12 noon  Rosenstiel 118 
Molecular Genetics Journal Club 
Jackie McDermott (Paradis Lab) 
Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts 
Ref: Loh KH, Stawski PS, Draycott AS, Udeshi ND, Lehrman EK, Wilton DK, Svinkina T, Deerinck TJ, Ellisman MH, Stevens B, Carr SA, Ting AY. Cell. 2016 Aug 25;166(5):12951307.e21. 
Denise Hilton (Goode Lab) 
Dynamic actin cycling through mitochondrial subpopulations locally regulates the fissionfusion balance within mitochondrial networks 
Ref: Moore AS, Wong YC, Simpson CL, Holzbaur EL. Nat Commun. 2016 Sep 30;7:12886 

Mon 11/7/16 3:30 pm  Volen 101 
Computational Linguistics Seminar (Computational Linguistics Seminar Series) 
Patrick Hanks (Professor of Lexicography, University of Wolverhampton, UK) 
Corpus Pattern Analysis 
Word Sense Disambiguation (WSD) continues to present insoluble problems for computers and linguists alike (though not, apparently, for ordinary language users). How can this paradox be explained? In this talk, I argue that the root of the problem lies in misguided reductionism. It is a mistake to try and tie meanings too closely to words in isolation. This is because words in isolation do not have much if any meaning as such; they have only meaning potential. Different aspects of a word's meaning potential are activated by different contexts. 
First of a series of three talks that explore how people use words to make meanings, and ask how meaning can be processed computationally. 
Hosted by James Pustejovsky 

Tue 11/8/16 12:30 pm  Gerstenzang 121 
M.R. Bauer Colloquium Series 
Gerald Rubin (Janelia) 
Learning and Memory in Drosophila 
Hosted by Michael Roshabsh, Leslie Griffith, Eve Marder 

Tue 11/8/16 1 pm  Goldsmith 226 
Combinatorics Seminar 
Ira Gessel (Brandeis University) 
An Introduction to Combinatorial Species 
The theory of combinatorial species is a method for counting labeled and unlabeled structures such as graphs of various types. In particular it provides a powerful alternative approach to problems traditionally solved by Pólya theory. I will discuss the basic definitions and examples, and describe the fundamental operations on species. I will also discuss the three fundamental generating functions associated with a species, in particular, the cycle index, which is a symmetric function associated with an action of the symmetric group. 
Hosted by Olivier Bernardi and Yan Zhuang 

Tue 11/8/16 4 pm  Abelson 131 
Physics Department Colloquium (Joint IGERT/Physics Dept Colloquium) 
Jeffrey Morris (CUNY) 
Friction and adhesion in colloids: Yielding, thickening, jamming 
Abstract: In recent work, we have shown [1,2] that frictional interactions provide a rational basis for both continuous and discontinuous shear thickening in viscous suspensions. When the repulsive forces (such as those due to electrostatic or steric colloidal stabilization) are overwhelmed by shearing forces, contact is assumed to occur, and the system transitions from a lowviscosity (lubricated) to a highviscosity (frictional) state. Contacting particles may experience both adhesive forces as well as friction. We will consider the influence of attractive forces at contact, in combination with the stabilizing repulsive forces. This combination of forces would be seen in the case of particles with van der Waals attraction in combination with colloidal stabilization. For sufficient attractive force a yield stress and shear thinning give way to the shear thickening response, a behavior observed in certain flocculated dispersions. At sufficient yield stress, the shear thickening is completely obscured, as the dispersions shear thins after yielding directly onto the highviscosity (frictional) plateau. The suggestion that a material may exhibit both yielding at low stress and jamming at large stress [3] is explored. 1. R. Seto, R. Mari, J. F. Morris & M. M. Denn 2013 Discontinuous shear thickening of frictional hardsphere suspensions. Phys. Rev. Lett. 111, 218301. 2. . R. Mari, R. Seto, J. F. Morris & M. M. Denn 2015 Discontinuous shear thickening in Brownian suspensions by dynamic simulation. Proc. National Acad. Sci. 112. 15326. 3. N. J. Wagner & J. F. Brady 2009 Shear thickening in colloidal dispersions. Phys. Today 62, 2732. Speaker Bio: Jeffrey F. Morris (City College of New York, CUNY; Levich Institute and Chemical Engineering): Ph.D. Caltech, 1995. Postdoc: Shell Research BV (KSLA, Amsterdam), 19941995; Georgia Tech: Assistant Professor, 1996 2002; Senior Scientific Advisor, Halliburton 20022004; City College of New York, CUNY: Associate Professor (20052008), Professor (2008Present), Chair of Chemical Engineering (1/20131/2016); Acting Director, Levich Institute (2015); Director, Levich Institute (2016).Jeff Morris is an Associate Editor of the Journal of Fluid Mechanics, and is on the Editorial Boards of the Journal of NonNewtonian Fluid Mechanics and the International Journal of Multiphase Flow. He authored the text A Physical Introduction to Suspension Dynamics, with E. Guazzelli. Research: Development of a fluid mechanical description appropriate for complex fluids, particularly suspensions and colloids, with a recent focus on the interaction of frictional interactions with viscous forces. Applying simulation and experiment, combined with ideas of statistical and continuum mechanics, the research seeks to develop understanding of flowinduced microstructure and the resulting mixture rheology. Of particular interest are rheologicallyinduced phenomena unique to mixtures, including bulk particle migration. In addition, the group has active projects in gashydrate emulsions. For present work see URL: http://wwwlevich.engr.ccny.cuny.edu/~jmorris/ Visiting positions: Morris has held Visiting Professor positions at Brown University (Applied Math) the Université de Paris Sud (at the Laboratory FAST) and Université de Provence (at the Laboratory IUSTI), and served as a visiting Director of Research at the CNRS, all in France, and is presently named as Chair d’Attractivité, Université De Toulouse 3 (Univ. Paul Sabatier). Honors: APS Fellow (Elected 2013); 2015 Journal of Rheology Publication Award; Ralph Powe Junior Faculty Award. Committee of Visitors, NSF DMR (2015); Advisory Board to ACS Petroleum Research Fund (20162018). Chair d’Attractivité, Université De Toulouse 3 (Univ. Paul Sabatier) 20162020. 
Hosted by Professor Bulbul Chakraborty 

Wed 11/9/16 12 noon  Rosenstiel 118 
Neurobiology Journal Club 
Yasu Shima (Brandeis University Nelson Lab) 
DivSeq: Singlenucleus RNASeq reveals dynamics of rare adult newborn neurons 
Ref: Habib et al., Science, 353(6302), 925928. (2016) 
Joseph Wachutka (Katz Lab) 
Social conflict resolution regulated by two dorsal habenular subregions in zebrafish 
Ref: Science 01 APR 2016 : 8790 

Wed 11/9/16 3:30 pm  Volen 101 
Computer Science Seminar (Computational Linguistics Seminar Series) 
Patrick Hanks (Professor of Lexicography, University of Wolverhampton, UK) 
Three Types of Semantic Resonance 
The third in a series of three talks to explore how people use words to make meanings, and ask how meaning can be processed computationally. Insofar as linguistics has had anything at all to say about meaning in language, it has tended to focus on literal meaning, of a kind found in the most boring scientific texts and technical user manuals. But nonliteral meaning has an important role, too, to play in communication and conversation. This talk will offer an exploration of three aspects of nonliteral meaning and various kinds of creativity. Wednesday, November 9, 2016 in Volen 101 at 3:30 pm. 
The thrid in a series of three talks that explore how people use words to make meanings, and ask how meaning can be processed computationally. 
Hosted by James Pustejovsky 

Thu 11/10/16 12 noon  Rosenstiel 118 
Psychology Department Brown Bag 
Wanbing Zhang (Aging, Culture, and Cognition Lab) 
TBA 
Jeremy Simon (Social Interaction & Motivation Lab) 
TBA 

Fri 11/11/16 11:15 am  Rosenstiel 118 
BiochemistryBiophysics Friday Lunchtime Pizza Talks 
Ken Dill (Stony Brook University) 
Cell behaviors are encoded in proteome physics, not just in the biology of the genes 
Hosted by Timo Street 

Fri 11/11/16 12:30 pm  Gerstenzang 123 
Molecular and Cell Biology & Neuroscience Student Seminars 
NO PIZZA TALKS  SfN meeting 

Fri 11/11/16 2 pm  Gerstenzang 122 
Chemistry Department Colloquium 
Tom Holme (Iowa State University) 
Research on measurements in the classroom and what it tells us about teaching and learning of chemistry 
Hosted by Klaus SchmidtRohr 

Mon 11/14/16 11 am  Abelson 307 
String Theory Seminar 
Washington Taylor (MIT) 
TBA 
Hosted by Professor Matthew Headrick 

Mon 11/14/16 12 noon  Rosenstiel 118 
Molecular Genetics Journal Club 
Aimee Shen (Molecular Microbiology, Tufts University School of Medicine) 
Assembly of spores by the bacterial pathogen Clostridium difficile 
Hosted by Avi Rodal 

Mon 11/14/16 4 pm  Gerstenzang 121 
Chemistry Department Colloquium 
Zhong Yin Zhang (Purdue University) 
Drugging the undruggable: therapeutic potential of targeting protein tyrosine phosphatases 
Hosted by Bing Xu/Liz Hedstrom 

Tue 11/15/16 12:30 pm  Gerstenzang 121 
Joint Biology/Neuroscience Colloquium 
James Bear (UNC Chapel Hill) 
Life without the Arp2/3 complex: What works, what doesn’t 
Hosted by Bruce Goode 

Tue 11/15/16 1 pm  Goldsmith 226 
Combinatorics Seminar 
Ira Gessel (Brandeis University) 
The KonvalinkaAmdeberhan conjecture and plethystic inverses 
Motivated by Billey, Konvalinka, and Matsen's formula for unlabeled tanglegrams, Tewodros Amdeberhan and Matjaž Konvalinka independently conjectured that a generalization of their formula always gives integers. I will prove their conjecture using the fact that the plethystic inverse of an integral symmetric function is integral, and I will discuss the conjectured Schur positivity of these symmetric functions, which are related to the Lyndon (primitive necklace) symmetric functions. 
Hosted by Olivier Bernardi and Yan Zhuang 

Tue 11/15/16 4 pm  Abelson 131 
Eisenbud Lecture Series in Mathematics and Physics ( ) 
Nigel Hitchin (University of Oxford) 
Algebraic curves and differential equations 
Abstract: Euler's equations for a spinning top are wellknown to be solvable by elliptic functions. They form the first example of a much wider range of equations, in particular Nahm's equations, which are solvable using algebraic curves of higher genus. Nahm's equations appear in various parts of differential geometry and physics, related to hyperk ̈ahler geometry and magnetic monopoles in particular. Loosely speaking, the equations are linearized on the Jacobian of the curve. However, there are many situations where that curve is singular or nonreduced and this viewpoint is no longer valid. The talk will discuss the geometry of what happens in some of these cases.Speaker Bio: Prof. Hitchin is a leader in differential geometry and mathematical physics, known for his many fundamental contributions to low dimensional topology, complex and algebraic geometry, mirror symmetry and string theory. He is a Fellow of the Royal Society and a recipient of numerous prestigious awards, including the Sylvester Medal of the Royal Society in 2000, the Polya Prize in 2002 and the Shaw Prize in Mathematical Sciences in 2016. 
Hosted by Professor Bong Lian 

Wed 11/16/16 4 pm  Lurias, Hassenfeld Conference Center 
Eisenbud Lecture Series in Mathematics and Physics (Lecture II) 
Nigel Hitchin (University of Oxford) 
Generalizing hyperbolic surfaces 
Abstract: The theory of Higgs bundles on a compact Riemann surface provided a natural setting for hyperbolic surfaces within the context of an SU(2)gauge theory with a complex Higgs field. Replacing the group SU(2) by the group of symplectic diffeomorphisms of the twosphere provides, thanks to work of Biquard, an infinitedimensional generalization of Teichm ̈uller space, but it is as yet unclear what type of geometry, generalizing hyperbolic metrics, on the surface this parametrizes. The lecture will investigate some of the questions and features involved.Speaker Bio: Prof. Hitchin is a leader in differential geometry and mathematical physics, known for his many fundamental contributions to low dimensional topology, complex and algebraic geometry, mirror symmetry and string theory. He is a Fellow of the Royal Society and a recipient of numerous prestigious awards, including the Sylvester Medal of the Royal Society in 2000, the Polya Prize in 2002 and the Shaw Prize in Mathematical Sciences in 2016. 
Hosted by Professor Bong Lian 

Thu 11/17/16 12 noon  
Psychology Department Colloquium (NIGMS Brain, Body & Behavior,NIA Cognitive Aging in social Context) 
Dr. Nancy Dennis (Penn State University) 
TBA 
TBA 
Hosted by Bob Sekuler 

Thu 11/17/16 2 pm  Volen 119 
Theory IGERT Seminar 
Daniel Ruberman (Brandeis) 
TBA 
Hosted by Prof. Albion Lawrence 

Thu 11/17/16 5:30 pm  Shapiro Science Center Atrium 
Brandeis Innovation Showcase 
SPROUT and SPARK grant recipienits 
2nd Annual Innovation Showcase 
Among the exhibits will be research projects from our SPROUT and SPARK grant recipients, information about internal and external competitions for Brandeis innovators, displays of notable Brandeis inventions and much more. 
Hosted by The Office of Technology Licensing and the Hassenfeld Family Innovation Center 

Fri 11/18/16 11 am  TBA 
Eisenbud Lecture Series in Mathematics and Physics (Lecture III) 
Nigel Hitchin (University of Oxford) 
Higgs bundles and mirror symmetry 
Abstract: The moduli space of Higgs bundles on a curve, together with its fibration structure as an integrable system, forms a natural example to examine the predictions of mirror symmetry in the approach of Strominger, Yau and Zaslow. The mirror for gauge group G is regarded as being the moduli space for the Langlands dual group LG. Of particular interest is the how this manifests itself in the duality of "branes" on each side. We consider in the talk cases arising from noncompact real forms of complex groups, and also Lagrangians arising from the existence of holomorphic spinor fields.Speaker Bio: Prof. Hitchin is a leader in differential geometry and mathematical physics, known for his many fundamental contributions to low dimensional topology, complex and algebraic geometry, mirror symmetry and string theory. He is a Fellow of the Royal Society and a recipient of numerous prestigious awards, including the Sylvester Medal of the Royal Society in 2000, the Polya Prize in 2002 and the Shaw Prize in Mathematical Sciences in 2016. 
Note time and location change to 1:30pm (original time was 4pm) 
Hosted by Professor Bong Lian 

Fri 11/18/16 11:15 am  Rosenstiel 118 
BiochemistryBiophysics Friday Lunchtime Pizza Talks 
Carson Thoreen (Yale Medical School) 
Translational control of growth by the mTOR pathway 
Hosted by Chris Miller 

Fri 11/18/16 12:30 pm  Gerstenzang 123 
Molecular and Cell Biology & Neuroscience Student Seminars 
Drew Sawyer (Marr Lab) 
Dan Acker (Paradis Lab) 

Mon 11/21/16 11 am  Abelson 307 
String Theory Seminar 
TBA 
TBA 

Mon 11/21/16 11 am  
Computational Neuroscience Journal Club 
Kanaka Rajan (Princeton University) 
Pizza at noon 

Mon 11/21/16 11 am  Abelson 307 
String Theory Seminar 
Harsha Hampapura (Brandeis University) 
TBA 
Hosted by Matthew Headrick 

Mon 11/21/16 12 noon  Rosenstiel 118 
Molecular Genetics Journal Club 
John Landers (Department of Neurology, University of Massachusetts Medical School) 
Genetics of Sporadic and Familial ALS 
Hosted by Bruce Goode 

Tue 11/22/16 4 pm  
Physics Department Colloquium 
No colloquium (Thanksgiving Week) 

Fri 11/25/16 12:30 pm  Gerstenzang 123 
Molecular and Cell Biology & Neuroscience Student Seminars 
NO PIZZA TALKS  Thanksgiving 
