Our laboratory is studying the three-dimensional structure of macromolecular machines,

organelles and cells using cryo-electron tomography.

We are focusing on the structure and function relationships of macromolecular complexes

in situ, i.e. in their native environment.

Areas of interest include the structure of eukaryotic flagella and the molecular motor

dynein, the cytoskeleton and bacteria, as well as the development of cryo-EM and image

processing techniques.