lab location:

Shapiro Science Center 1-08
(781)736-3176/3177
Interactive Map

shipping address:

Paradis Lab
Department of Biology
Lab Supplies & Receiving – Kalman
Brandeis University
415 South St.
Waltham, MA 02454

Available Positions

A postdoctoral position is available in the lab of Suzanne Paradis, PhD in the Department of Biology and Program in Neuroscience at Brandeis University in Waltham, MA. Research in our NIH-funded laboratory seeks to define the genes that instruct neurons to establish and modify their connectivity, with the overall goal of understanding how neural network dysfunction contributes to neurological disorders. We employ biochemistry, molecular biology, genetic, electrophysiology, and imaging approaches in rodents to accomplish this goal.

We are seeking a talented and motivated electrophysiologist who is interested in augmenting their physiology skills with training in molecular biology and mouse genetic techniques in the area of epilepsy. We recently discovered that Sema4D, signaling through its high affinity receptor PlexinB1, regulates inhibitory synapse formation on a rapid time scale (i.e. minutes to hours) both in vitro and in vivo. Further, Sema4D administration suppresses seizure activity in mouse models of epilepsy. We seek a neuroscientist interested in studying Sema4D-dependent changes in GABAergic synaptic transmission in order to understand mechanism by which Sema4D administration suppresses seizures.

The ideal candidate would have experience performing voltage-clamp recordings from acute hippocampal or cortical slices. However, any proficient electrophysiologist with an interest in synaptic physiology will be given serious consideration. Successful applicants will have a strong record of productivity and have published first author papers in internationally recognized journals. In addition, strong preference will be given to applicants that are eligible for appointment to an NIH T32 training grant (US citizen or permanent resident), are less than 24 months out from their PhD defense date, and are able to begin work by June 16, 2020.

Brandeis University, located 9 miles outside of Boston with easy commuting options, has a unique, collaborative life science research community spanning Biology, Neuroscience, Biochemistry, Biophysics and Chemistry. Our University benefits from many shared resources including core facilities, seminars, a strong neuroscience research community, and interdisciplinary training and research programs.

More information about the lab and our research can be found on the Paradis Lab website.

Interested candidates should send a curriculum vitae including email addresses for 3 references to paradis@brandeis.edu.