RSS Lab News

  • Neurons that make flies sleep
    Sleep is known to be regulated by both intrinsic (what time is it?) and environmental factors (is it hot today?). How exactly these factors are integrated at the cellular level is a hot topic for investigation, given the prevalence of sleep disorders. Researchers in the Rosbash and Griffith labs are pursuing the question in the […]
  • Sprout Award Winners Announced
    The recipients of the 6th annual Sprout Awards have been announced. There will be eight teams from labs in the Biology, Biochemistry, and Chemistry departments sharing the $100,000 in funding in FY 2017. The Sprout program’s grant pool was doubled this year in order to expand the support for the promising innovation and research that is […]
  • Four Brandeis Science Grads Receive 2016 NSF Graduate Fellowships
    A science education at Brandeis University can be a springboard to future science achievements. We would like to congratulate four of our science graduates who have received the prestigious National Science Foundation Graduate Research Fellowships for 2016. Noam Saper Noam was an outstanding student graduating summa cum laude with highest honors in Chemistry in 2015. […]
  • Brandeis will host Gene Expression and RNA Seminar (GEARS) meeting this October
    Gene Expression and RNA Seminars (GEARS) club is a monthly event that includes scientific talks on the Gene Expression, RNA and Chromatin. Every month it is held at a different institute in the Boston area. Brandeis University will be hosting the October GEARS meeting on Thursday, October 30 in Rosenstiel 118 from 6:30 – 7.30 […]
  • Hall, Rosbash and Young Share Shaw Prize in Life Science and Medicine
    The 10th annual Shaw Prize in Life Science and Medicine has been awarded jointly to Michael Rosbash and Jeffrey Hall of Brandeis and Michael Young of Rockefeller University. The trio are once again being honored for their discovery of molecular mechanisms underlying circadian rhythms. Hall is Emeritus Professor of Biology at Brandeis, and Rosbash is Peter Gruber […]

RSS Recent Publications

  • Circadian neuron feedback controls the Drosophila sleep-activity profile.
    Related Articles Circadian neuron feedback controls the Drosophila sleep-activity profile. Nature. 2016 Aug 1; Authors: Guo F, Yu J, Jung HJ, Abruzzi KC, Luo W, Griffith LC, Rosbash M Abstract Little is known about the ability of Drosophila circadian neurons to promote sleep. Here we show, using optogenetic manipulation and video recording, that a subset […]
  • Promiscuous or discriminating: Has the favored mRNA target of Fragile X Mental Retardation Protein been overlooked?
    Related Articles Promiscuous or discriminating: Has the favored mRNA target of Fragile X Mental Retardation Protein been overlooked? Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7009-11 Authors: McMahon AC, Rosbash M PMID: 27317743 [PubMed - in process]
  • Age-Related Reduction of Recovery Sleep and Arousal Threshold in Drosophila.
    Related Articles Age-Related Reduction of Recovery Sleep and Arousal Threshold in Drosophila. Sleep. 2016;39(8):1613-24 Authors: Vienne J, Spann R, Guo F, Rosbash M Abstract STUDY OBJECTIVES: Physiological studies show that aging affects both sleep quality and quantity in humans, and sleep complaints increase with age. Along with knowledge about the negative effects of poor sleep […]
  • mir-276a strengthens Drosophila circadian rhythms by regulating timeless expression.
    Related Articles mir-276a strengthens Drosophila circadian rhythms by regulating timeless expression. Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2965-72 Authors: Chen X, Rosbash M Abstract Circadian rhythms in metazoan eukaryotes are controlled by an endogenous molecular clock. It functions in many locations, including subsets of brain neurons (clock neurons) within the central nervous […]
  • TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins.
    Related Articles TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins. Cell. 2016 Apr 21;165(3):742-53 Authors: McMahon AC, Rahman R, Jin H, Shen JL, Fieldsend A, Luo W, Rosbash M Abstract RNA transcripts are bound and regulated by RNA-binding proteins (RBPs). Current methods for identifying in vivo targets of an RBP are imperfect […]