• Lateral view of merged Nomarski and fluorescent images of a wild-type (E) or alr-1(oy42) animal (F) expressing an odr-10::gfp fusion gene that allows visualization of the AWA sensory dendrite. (Melkman et al., 2005)

• Nokes EB, Van Der Linden AM, Winslow C, Mukhopadhyay S, Ma K, Sengupta P. (2009) Cis-regulatory mechanisms of gene expression in an olfactory neuron type in Caenorhabditis elegans. Dev Dyn. 238: 3080-3092. [PubMed]
• Mukhopadhyay, S., Lu, Y., Shaham, S., and Sengupta, P. (2008). Sensory signaling-dependent remodeling of olfactory cilia architecture in C. elegans. Dev Cell 14, 762-774. [PubMed]
• Omori, Y., Zhao, C., Saras, A., Mukhopadhyay, S., Kim, W., Furukawa, T., Sengupta, P., Veraksa, A., and Malicki, J. (2008). Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat Cell Biol 10, 437-444. [PubMed]
• Bauer Huang, S.L., Saheki, Y., VanHoven, M.K., Torayama, I., Ishihara, T., Katsura, I., van der Linden, A., Sengupta, P., and Bargmann, C.I. (2007). Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans. Neural Develop 2, 24. [PubMed]
• Mukhopadhyay, S., Lu, Y., Qin, H., Lanjuin, A., Shaham, S., and Sengupta, P. (2007). Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans. EMBO J 26, 2966-2980. [PubMed]
• Lanjuin, A., Claggett, J., Shibuya, M., Hunter, C.P., and Sengupta, P. (2006). Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1. Dev Biol 290, 139-151. [PubMed]
• Kim, K., Colosimo, M.E., Yeung, H., and Sengupta, P. (2005). The UNC-3 Olf/EBF protein represses alternate neuronal programs to specify chemosensory neuron identity. Dev Biol 286, 136-148. [PubMed]
• Melkman, T., and Sengupta, P. (2005). Regulation of chemosensory and GABAergic motor neuron development by the C. elegans Aristaless/Arx homolog alr-1. Development 132, 1935-1949. [PubMed]
• Colosimo, M.E., Tran, S., and Sengupta, P. (2003). The divergent orphan nuclear receptor ODR-7 regulates olfactory neuron gene expression via multiple mechanisms in Caenorhabditis elegans. Genetics 165, 1779-1791. [PubMed]
• Lanjuin, A., VanHoven, M.K., Bargmann, C.I., Thompson, J.K., and Sengupta, P. (2003). Otx/otd homeobox genes specify distinct sensory neuron identities in C. elegans. Dev Cell 5, 621-633. [PubMed]
• Lanjuin, A., and Sengupta, P. (2002). Regulation of chemosensory receptor expression and sensory signaling by the KIN-29 Ser/Thr kinase. Neuron 33, 369-381. [PubMed]
• Colosimo, M.E., Brown, A., Mukhopadhyay, S., Gabel, C., Lanjuin, A.E., Samuel, A.D., and Sengupta, P. (2004). Identification of thermosensory and olfactory neuron-specific genes via expression profiling of single neuron types. Curr Biol 14, 2245-2251. [PubMed]
• Satterlee, J.S., Sasakura, H., Kuhara, A., Berkeley, M., Mori, I., and Sengupta, P. (2001). Specification of thermosensory neuron fate in C. elegans requires ttx-1, a homolog of otd/Otx. Neuron 31, 943-956. [PubMed]
• Sarafi-Reinach, T.R., Melkman, T., Hobert, O., and Sengupta, P. (2001). The lin-11 LIM homeobox gene specifies olfactory and chemosensory neuron fates in C. elegans. Development 128, 3269-3281. [PubMed]
• Sarafi-Reinach, T.R., and Sengupta, P. (2000). The forkhead domain gene unc-130 generates chemosensory neuron diversity in C. elegans. Genes Dev 14, 2472-2485. [PubMed]
• Miyabayashi, T., Palfreyman, M.T., Sluder, A.E., Slack, F., and Sengupta, P. (1999). Expression and function of members of a divergent nuclear receptor family in Caenorhabditis elegans. Dev Biol 215, 314-331. [PubMed]

Reviews

• Lanjuin, A., and Sengupta, P. (2004). Specification of chemosensory neuron subtype identities in Caenorhabditis elegans. Curr Opin Neurobiol 14, 22-30. (Review) [PubMed]
• Sengupta, P. (2004). Taking sides in the nervous system with miRNA. Nat Neurosci 7, 100-102. (Review) [PubMed]
• Melkman, T., and Sengupta, P. (2004). The worm's sense of smell. Development of functional diversity in the chemosensory system of Caenorhabditis elegans. Dev Biol 265, 302-319. (Review) [PubMed]

[Back to Top]

Expression of an sra-6::gfp transgene is reduced in the ASH and ASI sensory neurons of daf-8(oy8) mutants. (Nolan et al., 2002)

• Kim K, Sato K, Shibuya M, Zeiger DM, Butcher RA, Ragains JR, Clardy J, Touhara K, Sengupta P (2009) Two Chemoreceptors Mediate Developmental Effects of Dauer Pheromone in C. elegans. Science. 326: 994-998. [PubMed]
• van der Linden, A.M., Wiener, S., You, Y-J., Kim, K., Avery L., and Sengupta, P. (2008) The EGL-4 PKG acts with the KIN-29 SIK and KIN-2 PKA to regulate chemoreceptor gene expression and sensory behaviors in C. elegans. Genetics. 180, 1475-91. [PubMed]
• van der Linden, A.M., Nolan, K.M., and Sengupta, P. (2007). KIN-29 SIK regulates chemoreceptor gene expression via an MEF2 transcription factor and a class II HDAC. EMBO J 26, 358-370. [PubMed]
• Fujiwara, M., Sengupta, P., and McIntire, S.L. (2002). Regulation of body size and behavioral state of C. elegans by sensory perception and the EGL-4 cGMP-dependent protein kinase. Neuron 36, 1091-1102. [PubMed]
• Nolan, K.M., Sarafi-Reinach, T.R., Horne, J.G., Saffer, A.M., and Sengupta, P. (2002). The DAF-7 TGF-beta signaling pathway regulates chemosensory receptor gene expression in C. elegans. Genes Dev 16, 3061-3073. [PubMed]
• Lanjuin, A., and Sengupta, P. (2002) The KIN-29 Ser/Thr kinase regulates chemosensory receptor expression and neuroendocrine signaling in C. elegans. Neuron 33, 369-81. [PubMed]
• Chou, J.H., Bargmann, C.I., and Sengupta, P. (2001). The Caenorhabditis elegans odr-2 gene encodes a novel Ly-6-related protein required for olfaction. Genetics 157, 211-224. [PubMed]
• Daniels, S.A., Ailion, M., Thomas, J.H., and Sengupta, P. (2000). egl-4 acts through a transforming growth factor-beta/SMAD pathway in Caenorhabditis elegans to regulate multiple neuronal circuits in response to sensory cues. Genetics 156, 123-141. [PubMed]
• Sengupta, P. and Carlson, J. (2000) Genetic models in chemoreception in Neurobiology of Taste and Smell. (T.E. Finger, W.L. Silver and D. Restrepo, eds.) pp 41-72. Wiley Press, New York, USA.

Reviews

• Sengupta, P. (2007). Smell: the worm turns. Nature 450, 35-36. (Review) [PubMed]
• Sengupta, P., and Thomas, J.H. (2007). From eye of newt to chemical structure. Nat Chem Biol 3, 368-369. (Review) [PubMed]
• Sengupta, P. (2007). Generation and modulation of chemosensory behaviors in C. elegans. Pflugers Arch 454, 721-734. (Review) [PubMed]
• Sengupta, P. (2002). Chemosensation: tasting with the tail. Curr Biol 12, R386-388. (Review) [PubMed]
• Sengupta, P. (1997). Cellular and molecular analyses of olfactory behavior in C. elegans. Semin Cell Dev Biol 8, 153-161. (Review) [PubMed]

[Back to Top]

• Isothermal tracks made by wild-type worms cultivated overnight at 20°C and placed on a thermal gradient. (Biron et al., 2006)

  Biron, D.*, Wasserman, S.*, Thomas, J.H., Samuel, A.D., and Sengupta, P. (2008). An olfactory neuron responds stochastically to temperature and modulates Caenorhabditis elegans thermotactic behavior. Proc Natl Acad Sci U S A 105, 11002-11007. [PubMed] (*equal contributors)
• Chi, C.A., Clark, D.A., Lee, S., Biron, D., Luo, L., Gabel, C.V., Brown, J., Sengupta, P., and Samuel, A.D. (2007). Temperature and food mediate long-term thermotactic behavioral plasticity by association-independent mechanisms in C. elegans. J Exp Biol 210, 4043-4052. [PubMed]
• Biron, D., Shibuya, M., Gabel, C., Wasserman, S.M., Clark, D.A., Brown, A., Sengupta, P., and Samuel, A.D. (2006). A diacylglycerol kinase modulates long-term thermotactic behavioral plasticity in C. elegans. Nat Neurosci 9, 1499-1505. [PubMed]
• Clark, D.A., Biron, D., Sengupta, P., and Samuel, A.D. (2006). The AFD sensory neurons encode multiple functions underlying thermotactic behavior in Caenorhabditis elegans. J Neurosci 26, 7444-7451. [PubMed]
• Inada, H., Ito, H., Satterlee, J., Sengupta, P., Matsumoto, K., and Mori, I. (2006). Identification of guanylyl cyclases that function in thermosensory neurons of Caenorhabditis elegans. Genetics 172, 2239-2252. [PubMed]
• Samuel, A.D., and Sengupta, P. (2005). Sensorimotor integration: locating locomotion in neural circuits. Curr Biol 15, R341-343. [PubMed]
• Colosimo, M.E., Brown, A., Mukhopadhyay, S., Gabel, C., Lanjuin, A.E., Samuel, A.D., and Sengupta, P. (2004). Identification of thermosensory and olfactory neuron-specific genes via expression profiling of single neuron types. Curr Biol 14, 2245-2251. [PubMed]
• Satterlee, J.S., Ryu, W.S., and Sengupta, P. (2004). The CMK-1 CaMKI and the TAX-4 Cyclic nucleotide-gated channel regulate thermosensory neuron gene expression and function in C. elegans. Curr Biol 14, 62-68. [PubMed]

[Back to Top]