Turrigiano Lab Publications:
Visual deprivation during a critical period selectively suppresses L5 pyramidal excitability by preventing the induction of intrinsic plasticity. Nataraj K, Le Roux N, Nahmani M, Lefort S, Turrigiano GG. Neuron. 2010 Nov 18; 68(4): 750-62. (COVER) PDF

Tumor Necrosis Factor-α signaling maintains the ability of cortical synapses to express synaptic scaling. Steinmetz CC and Turrigiano GG. J Neuroscience. 2010 Nov 3; 30(44):14685-90. PDF

Critical period for inhibitory plasticity in rodent binocular V1
. Maffei A, Lambo ME, Turrigiano GG. J Neuroscience. 2010 Mar 3;30(9):3304-9. PDF
Synaptic scaling requires the GluR2 subunit of the AMPA receptor. Gainey MA, Hurvitz-Wolff JR, Lambo ME, Turrigiano GG. J Neuroscience. 2009 May 20;29(20):6479-89. PDF

Experience-dependent regulation of TrkB isoforms in rodent visual cortex. Bracken BK, Turrigiano GG. Dev Neurobiology. 2009 Apr;69(5):267-78. PDF
Strength through diversity. Nelson SB, Turrigiano GG. Neuron. 2008 Nov 6;60(3) 477-82. Review. PDF

The self-tuning neuron: synaptic scaling of excitatory synapses
. Turrigiano GG. Cell. 2008 Oct 31;135(3):422-35. PDF

Multiple modes of network homeostasis in visual cortical layer 2/3. Maffei A, Turrigiano GG. J Neuroscience. 2008 Apr 23;28(17):4377-84. PDF

The age of plasticity: developmental regulation of synaptic plasticity in neocortical microcircuits. Maffei A, Turrigiano GG. Prog Brain Res. 2008;169:211-23. Review. PDF

Rapid synaptic scaling induced by changes in postsynaptic firing. Ibata K, Sun Q, Turrigiano GG. Neuron. 2008 Mar 27;57(6):819-26. PDF

Dynamics underlying synaptic gain between pairs of cortical pyramidal neurons. Pratt, KG, Taft C, Burbea M, Turrigiano GG. 2008. Developmental Neurobiology. 2008 Feb 1;68(2):143-51. PDF
Multiple forms of long-term plasticity at unitary neocortical layer 5 synapses. Sjöström PJ, Turrigiano GG, Nelson SB. Neuropharmacology. 2007 Jan;52(1):176-84. PDF

Homeostatic signaling: the positive side of negative feedback. Turrigiano G. Current Opinion Neurobiology. 2007 Jun;17(3):318-24. PDF

The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Giorgi C, Yeo GW, Stone ME, Katz DB, Burge C, Turrigiano G, Moore MJ. Cell. 2007 Jul 13 13; 130(1):179-91. PDF
More than a sidekick: glia and homeostatic synaptic plasticity. Turrigiano GG. Current Opinion Neurobiology. 2006 Oct;12(10):458-60. PDF

Potentiation of cortical inhibition by visual deprivation. Maffei A, Nataraj K, Nelson SB, Turrigiano GG. Nature. 2006 Sep 7;443(7107):81-4. PDF

Temporal regulation of the expression locus of homeostatic plasticity. Wierenga CJ, Walsh MF, Turrigiano GG. J Neurophysiology. 2006 Oct;96(4):2127-33. PDF
Postsynaptic expression of homeostatic plasticity at neocortical synapses. Wierenga CJ, Ibata K, Turrigiano GG. J Neuroscience. 2005 Mar 16;25(11):2895-905. PDF
Selective reconfiguration of layer 4 visual cortical circuitry by visual deprivation. Maffei A, Nelson SB, Turrigiano GG. Nature Neuroscience. 2004 Dec;7(12):1353-9. PDF

Endocannabinoid-dependent neocortical layer-5 LTD in the absence of postsynaptic spiking. Sjostrom PJ, Turrigiano GG, Nelson SB. J Neurophysiology. 2004 Dec;92(6):3338-43. PDF

A proportional but slower NMDA potentiation follows AMPA potentiation in LTP. Watt AJ, Sjostrom PJ, Hausser M, Nelson SB, Turrigiano GG. Nature Neuroscience. 2004 May;7(5):518-24. PDF

Long-term Potentiation of Intrinsic Excitability in LV Visual Cortical Neurons. Cudmore RH, Turrigiano GG. J Neurophysiology. 2004 Jul;92(1):341-8. PDF

Homeostatic plasticity in the developing nervous system. Turrigiano GG, Nelson SB. Nature Reviews Neuroscience. 2004 5:97-107. PDF
Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors. Sjostrom PJ, Turrigiano GG, Nelson SB. Neuron. 2003 Aug14 39(4):641-54. PDF

Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII. Pratt KG, Watt AJ, Griffith LC, Nelson SB, Turrigiano GG. Neuron. 2003 Jul 17;39(2):269-81. PDF
Critical Periods for Experience-dependent synaptic scaling in visual cortex. Desai NS, Cudmore, R.H, Nelson SB, and Turrigiano GG. Nature Neuroscience. 2002 Aug;5(8):783-789. PDF

Activity deprivation reduces miniature IPSC amplitude by decreasing the number of postsynaptic GABA(A) receptors clustered at neocortical synapses
. Kilman V, van Rossum MC, Turrigiano GG. J Neuroscience. 2002 Feb 15;22(4):1328-37. PDF

Postsynaptic depolarization scales quantal amplitudes in cortical pyramidal neurons
. Leslie KR, Nelson SB, Turrigiano GG. J Neuroscience. 2001 Oct 1;21(19):RC170. PDF

Activity coregulates quantal AMPA and NMDA currents at neocortical synapses
. Watt AJ, van Rossum MC, MacLeod KM, Nelson SB, Turrigiano GG. Neuron. 2000 Jun;26(3):659-70. PDF

Stable Hebbian learning from spike timing-dependent plasticity
. van Rossum MC, Bi GQ, Turrigiano GG.J Neuroscience. 2000 Dec 1;20(23):8812-21. PDF
BDNF regulates the intrinsic excitability of cortical neurons. Desai NS, Rutherford LC, Turrigiano GG. Learning and Memory. 1999 May-Jun;6(3):284-91. PDF

Plasticity in the intrinsic excitability of neocortical pyramidal neurons
. Desai, N.S., Rutherford, L.C., and Turrigiano, G.G. Nature Neuroscience 1999. 2:515-520. PDF

BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. Rutherford LC, Nelson SB, Turrigiano GG. Neuron. 1998 Sep;21(3):521-30. PDF

Activity-dependent scaling of quantal amplitude in neocortical neurons. Turrigiano GG, Leslie KR, Desai NS, Rutherford LC, Nelson SB. Nature. 1998 Feb 26;391(6670):892-6. PDF
Regional and temporal specificity of intrinsic plasticity mechanisms in rodent primary visual cortex. Nataraj, K. and Turrigiano G. J Neurosci. 2011 Dec 7; 31(49): 17932-40. PDF

PSD- 95 and PSD-93 play critical but distinct roles in synaptic scaling up and down
. Sun Q and Turrigiano GG. J Neuroscience. 2011 May 4; 31(18): 6800-6808. PDF

Too many cooks? Intrinsic and synaptic homeostatic mechanisms in cortical circuit refinement.
Turrigiano G. Annu Rev Neurosci. 2011;34:89-103. PDF
A Critical and Cell-Autonomous Role for MeCP2 in Synaptic Scaling Up. Blackman MP, Djukic B, Nelson SB, Turrigiano GG. J Neurosci. 2012 Sep 26;32(39):13529-36. PDF

Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function. Turrigiano G., Cold Spring Harb Perspect Biol. 2012 Jan 1;4(1):a005736. Review. PDF

PSD-95 promotes the stabilization of young synaptic contacts. Taft CE, Turrigiano GG. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633). PDF

Long-Term inhibitory plasticity in visual cortical layer 4 switches sign at the opening of the critical period
. Lefort S, Gray AC, Turrigiano GG. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47). PDF

Firing rate homeostasis in visual cortex of freely behaving rodents
. Hengen K, Lambo ME, Van Hooser SD, Katz DB, and Turrigiano GG. Neuron. 2013 Oct 16;80(2):335-342. (COVER) PDF

How to scale down postsynaptic strength
. Tatavarty V, Sun Q, Turrigiano GG. J Neurosci. 2013 Aug 7;33(32):13179-13189. PDF

Synaptic and intrinsic homeostatic mechanisms cooperate to increase L2/3 pyramidal neuron excitability during a late phase of cirical period plasticity. Lambo ME and Turrigiano GG. J Neurosci 2013 May 15;33(20):8810-8819. PDF
Deprivation-induced strengthening of presynaptic and postsynaptic inhibitory transmission in layer 4 of visual cortex during the critical period. Nahmani, M and Turrigiano, GG. J Neurosci. 2014 Feb 12:34(7):2571-82. (COVER) PDF
Adult cortical plasticity following injury: Recapitulation of critical period mechanisms? Nahmani, M and Turrigiano, GG. Neuroscience. 2014 May 1. poi:S0306-4522(14)00331-5.
Regulation of glutamate receptor internalization by the spine cytoskeleton is mediated by its PKA-dependent association with CPG2. Loebrich S, Djukic B, Tong ZJ, Cottrell JR, Turrigiano GG, Nedivi E. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4548-56. PDF
Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade. Gainey MA, Tatavarty V, Nahmani M, Lin H and Turrigiano GG. Proc Natl Acad Sci U S A. 2015 Jun 24.
Optogenetics: 10 years after ChR2 in neurons--views from the community. Adamantidis A, Arber S, Bains JS, Bamberg E, Bonci A, Buzsáki G, Cardin JA, Costa RM, Dan Y, Goda Y, Graybiel AM, Häusser M, Hegemann P, Huguenard JR, Insel TR, Janak PH, Johnston D, Josselyn SA, Koch C, Kreitzer AC, Lüscher C, Malenka RC, Miesenböck G, Nagel G, Roska B, Schnitzer MJ, Shenoy KV, Soltesz I, Sternson SM, Tsien RW, Tsien RY, Turrigiano GG, Tye KM, Wilson RI. Nat Neurosci. 2015 Sep;18(9):1202-12.
Neurobiology: Keeping a lid on it. Nahmani, M and Turrigiano, G. Nature. 2014 Jul 17;511(7509):297-8.
Neuronal Firing Rate Homeostasis Is Inhibited by Sleep and Promoted by Wake. Hengen KB, Pacheco, AT, McGregor JN, VanHooser SD and Turrigiano GG. Cell. 2016 Mar; 165: 1-12.