Lab of Jeff Gelles Department of Biochemistry at Brandeis University

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Movies Doing single molecule studies on molecular motors allows us to monitor movement and other processes in real time. Some examples of the things we are able to see are listed below. "Transcription against an Applied Force" movie Kinesin & AMP-PNP: The Movie DNA Translocation by RecBCD Helicase/Nuclease Brownian motion of DNA-tethered beads (5 Mb) Visualization of E. coli RNA polymerase transcription elongation by the tethered particle motion (TPM) technique (13 Mb)